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Table 2 Characteristics of the study population in the present study according to stroke and ICAS status

From: Association of peripheral neutrophil count with intracranial atherosclerotic stenosis

 With stroke(n = 1363)P-valueWithout stroke(n = 1484)P-value
With ICAS(n = 474)Without ICAS(n = 889)With ICAS(n = 283)Without ICAS(n = 1201)
Characteristics
 Age, mean ± SD, y69.15 ± 11.8581368.07 ± 11.533260.066569.3 ± 11.1768.2 ± 10.580.0667
 Male, n (%)291 (61.39%)544 (61.19%)0.9424170 (60.07%)734 (61.12%)0.7458
Hematological examinations
 Lipoprotein, median (IQR), mg/dL17.14 (7.36–31.66)15.84 (7.20–28.83)0.240815.250 (6.605–27.635)13.02 (5.92–25.15)0.0977
 Triglyceride, median (IQR), mmol/L1.3000 (0.9925–1.7300)1.320 (0.980–1.850)0.60361.230 (0.930–1.785)1.210 (0.880–1.750)0.7941
 Total cholesterol, median (IQR), mmol/L5.020 (4.162–5.800)5.040 (4.240–5.940)0.39624.510 (3.710–5.395)4.770 (4.070–5.490)0.0064
 HDL, median (IQR), mmol/L1.055 (0.910–1.280)1.130 (0.970–1.320)0.00101.060 (0.885–1.280)1.130 (0.960–1.340)0.0002
 LDL, median (IQR), mmol/L3.105 (2.493–3.610)3.120 (2.580–3.730)0.32642.800 (2.070–3.425)2.870 (2.360–3.410)0.0364
 Neutrophils, median (IQR), (per 109/L)4.320 (3.493–5.880)3.990 (3.150–5.040)< 0.00013.670 (2.850–4.625)3.420 (2.750–4.270)0.0097
 Lymphocytes, median (IQR), (per 109/L)1.835 (1.433–2.348)1.950 (1.510–2.430)0.02881.810 (1.425–2.385)1.990 (1.580–2.470)0.0018
 NLR, median (IQR)2.270 (1.712–3.522)1.970 (1.490–2.840)< 0.00011.830 (1.345–2.590)1.680 (1.280–2.330)0.0025
 Glucose,median(IQR), mmol/L5.845 (4.770–7.670)5.390 (4.580–7.290)0.00675.810 (4.850–8.500)5.200 (4.660–6.120)< 0.0001
Medical history, n (%)
 Hypertension, n (%),381 (80.38%)655 (73.68%)0.0058232 (82.27%)862 (58.09%)0.0005
 Diabetes mellitus, n (%)213 (44.97%)292 (32.85%)< 0.0001100 (35.34%)340 (28.31%)0.0199
 Coronary Heart Disease, n (%)164 (34.60%)270 (30.37%)0.1105110 (38.87%)497 (41.38%)0.4392
 Smoking, n (%)152 (32.07%)327 (36.78%)0.0825100 (35.34%)332 (22.37%)0.0104
 Alcohol use, n (%)108 (22.78%)237 (26.66%)0.117266 (23.32%)203 (13.68%)0.0117
  1. Abbreviations: IQR interquartile range, ICAS intracranial atherosclerotic stenosis, NLR neutrophil to lymphocyte ratio, SD standard deviation, HDL high-density lipoprotein, LDL low-density lipoprotein