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Table 2 Characteristics of the study population in the present study according to stroke and ICAS status

From: Association of peripheral neutrophil count with intracranial atherosclerotic stenosis

 

With stroke(n = 1363)

P-value

Without stroke(n = 1484)

P-value

With ICAS(n = 474)

Without ICAS(n = 889)

With ICAS(n = 283)

Without ICAS(n = 1201)

Characteristics

 Age, mean ± SD, y

69.15 ± 11.85813

68.07 ± 11.53326

0.0665

69.3 ± 11.17

68.2 ± 10.58

0.0667

 Male, n (%)

291 (61.39%)

544 (61.19%)

0.9424

170 (60.07%)

734 (61.12%)

0.7458

Hematological examinations

 Lipoprotein, median (IQR), mg/dL

17.14 (7.36–31.66)

15.84 (7.20–28.83)

0.2408

15.250 (6.605–27.635)

13.02 (5.92–25.15)

0.0977

 Triglyceride, median (IQR), mmol/L

1.3000 (0.9925–1.7300)

1.320 (0.980–1.850)

0.6036

1.230 (0.930–1.785)

1.210 (0.880–1.750)

0.7941

 Total cholesterol, median (IQR), mmol/L

5.020 (4.162–5.800)

5.040 (4.240–5.940)

0.3962

4.510 (3.710–5.395)

4.770 (4.070–5.490)

0.0064

 HDL, median (IQR), mmol/L

1.055 (0.910–1.280)

1.130 (0.970–1.320)

0.0010

1.060 (0.885–1.280)

1.130 (0.960–1.340)

0.0002

 LDL, median (IQR), mmol/L

3.105 (2.493–3.610)

3.120 (2.580–3.730)

0.3264

2.800 (2.070–3.425)

2.870 (2.360–3.410)

0.0364

 Neutrophils, median (IQR), (per 109/L)

4.320 (3.493–5.880)

3.990 (3.150–5.040)

< 0.0001

3.670 (2.850–4.625)

3.420 (2.750–4.270)

0.0097

 Lymphocytes, median (IQR), (per 109/L)

1.835 (1.433–2.348)

1.950 (1.510–2.430)

0.0288

1.810 (1.425–2.385)

1.990 (1.580–2.470)

0.0018

 NLR, median (IQR)

2.270 (1.712–3.522)

1.970 (1.490–2.840)

< 0.0001

1.830 (1.345–2.590)

1.680 (1.280–2.330)

0.0025

 Glucose,median(IQR), mmol/L

5.845 (4.770–7.670)

5.390 (4.580–7.290)

0.0067

5.810 (4.850–8.500)

5.200 (4.660–6.120)

< 0.0001

Medical history, n (%)

 Hypertension, n (%),

381 (80.38%)

655 (73.68%)

0.0058

232 (82.27%)

862 (58.09%)

0.0005

 Diabetes mellitus, n (%)

213 (44.97%)

292 (32.85%)

< 0.0001

100 (35.34%)

340 (28.31%)

0.0199

 Coronary Heart Disease, n (%)

164 (34.60%)

270 (30.37%)

0.1105

110 (38.87%)

497 (41.38%)

0.4392

 Smoking, n (%)

152 (32.07%)

327 (36.78%)

0.0825

100 (35.34%)

332 (22.37%)

0.0104

 Alcohol use, n (%)

108 (22.78%)

237 (26.66%)

0.1172

66 (23.32%)

203 (13.68%)

0.0117

  1. Abbreviations: IQR interquartile range, ICAS intracranial atherosclerotic stenosis, NLR neutrophil to lymphocyte ratio, SD standard deviation, HDL high-density lipoprotein, LDL low-density lipoprotein