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Table 3 Logistic regression analysis of the association between neutrophil count and intracranial atherosclerotic stenosis according to quartiles of neutrophil count

From: Association of peripheral neutrophil count with intracranial atherosclerotic stenosis

 

Unadjusted

Multivariate Analysis

OR

95%CI

P-value

OR

95%CI

P-value

With stroke

 Neutrophil(total)

1.18

1.11–1.25

< 0.0001

1.22

1.12–1.34

< 0.0001

 Quartile 1 (< 3.23)

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 Quartile 2 (3.23–4.09)

1.18

0.85–1.64

0.3310

1.44

1.00–2.08

0.0499

 Quartile 3 (4.10–5.40)

1.27

0.91–1.75

0.1560

1.89

1.26–2.86

0.0024

 Quartile 4 (> 5.40)

2.17

1.58–2.99

< 0.0001

2.82

1.79–4.48

< 0.0001

Without stroke

 Neutrophil(total)

1.10

1.01–1.19

0.0205

1.19

1.03–1.38

0.0214

 Quartile 1 (< 2.77)

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 Quartile 2 (2.77–3.46)

0.94

0.64–1.39

0.7632

0.91

0.60–1.39

0.6731

 Quartile 3 (3.47–4.32)

1.37

0.95–1.98

0.0910

1.39

0.92–2.11

0.1228

 Quartile 4 (> 4.32)

1.39

0.96–2.01

0.0807

1.47

0.89–2.43

0.1302

Total

 Neutrophil(total)

1.19

1.14–1.25

< 0.0001

1.24

1.16–1.32

< 0.0001

 Quartile 1 (< 2.94)

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 Quartile 2 (2.94–3.74)

1.04

0.81–1.35

0.7390

1.02

0.78–1.34

0.8924

 Quartile 3 (3.75–4.80)

1.63

1.28–2.08

< 0.0001

1.81

1.39–2.37

< 0.0001

 Quartile 4 (> 4.80)

2.09

1.65–2.66

< 0.0001

2.29

1.70–3.10

< 0.0001

  1. Abbreviations: OR Odd Ratio, CI Confidence Interval, ICAS intracranial atherosclerotic stenosis. In the group with stroke: adjusted for high-density lipoprotein, Lymphocytes, neutrophil to lymphocyte ratio, hypertension, diabetes mellitus, glycemia levels. In the group without stroke: adjusted for total cholesterol, high-density lipoprotein, low-density lipoprotein, lymphocytes, neutrophil to lymphocyte ratio, hypertension, diabetes mellitus, smoking, alcohol use, glycemia levels. Total: adjusted for lipoprotein, triglyceride, total cholesterol, high-density lipoprotein, low-density lipoprotein, neutrophil to lymphocyte ratio, diabetes mellitus, smoking, alcohol use, coronary heart disease, glycemia levels. In the group with stroke: among stroke with ICAS and stroke without ICAS groups; In the group without stroke: among non-stroke with ICAS and non-stroke without ICAS groups; Total: among groups with and without stroke