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Table 4 Baseline characteristics, interventional and outcome parameters according to the proposed criteria of the ASA/AHA (n = 257)

From: Stroke patients treated by thrombectomy in real life differ from cohorts of the clinical trials: a prospective observational study

 

ASA/AHA-group

n = 91

Non-ASA/AHA-group

n = 166

P values

Baseline characteristics

Age (years) - median (IQR)

74 (63–80)

75 (64–81.25)

0.439

Male – n (%)

46 (50.5)

86 (51.8)

0.847

Risk factors - n (%)

 Arterial hypertension

58 (63.7)

117 (70.5)

0.267

 Hyperlipidemia

17 (18.7)

23 (13.9)

0.307

 Diabetes mellitus

16 (17.6)

29 (17.5)

0.982

 Atrial fibrillation

41 (45.1)

53 (31.9)

0.037*

Stroke etiology – n (%)

  

0.356

 Atrial fibrillation

45 (49.5)

69 (41.6)

 

 Atherosclerosis

35 (38.5)

72 (43.4)

 

  ICA stenosis (> 70%)

20 (22.0)

20 (12.0)

 

 Dissection

2 (2.2)

1 (0.6)

 

 Other

6 (6.6)

11 (6.6)

 

 Undetermined

3 (3.3)

13 (7.8)

 

Anticoagulation before admission – n (%)

25 (27.5)

25 (15.1)

0.016*

Baseline NIHSS – median (IQR)

16 (13–19)

16 (11–21)

0.864

mRS before admission - median (IQR)

0 (0–0)

0 (0–1) (n = 165)

< 0.001*

Ship – n (%)

62 (68.1)

101 (60.8)

0.246

Intravenous thrombolysis – n (%)

58 (63.7)

95 (57.2)

0.309

Imaging characteristics

 ASPECTS – median (IQR)

8 (7–9)

7 (5–8)(n = 121)

< 0.001*

Workflow times

 Symptom onset to groin puncture (min) – median (IQR) (n = 74)

235 (187–291) (n = 78)

250 (176–334) (n = 84)

0.118

 Symptom onset to recanalization (min) – median (IQR) (n = 64)

284 (215–342) (n = 65)

318 (248–400) (n = 71)

0.024*

Procedural and outcome parameters

mTICI 2b/3 – n (%)

68 (74.7)

117 (70.5)

0.469

ICH – n (%)

15 (16.5)

30 (18.1)

0.749

sICH – n (%)

3 (3.3)

8 (4.8)

0.751

mRS at 90 days – median (IQR)

4 (1–5) (n = 84)

5 (3–6) (n = 158)

0.006*

  1. Abbreviations: ASA American Stroke Association, AHA American Heart Association, NIHSS National Institutes of Health Stroke Scale, IQR Interquartile range, ASPECTS Alberta Stroke Program Early CT Score, mRS Modified Rankin Scale, mTICI Modified Thrombolysis in Cerebral Infarction Score, ICH Intracerebral hemorrhage, sICH Symptomatic intracerebral hemorrhage
  2. * significant