Cytokine dysregulation persists in childhood post Neonatal Encephalopathy

BMC Neurology

Table 1 Demographics of infants with NE

Variables	NE 0/1 (n = 13)	NE- II/III (n = 24)	p- value (95% CI)
GA (wks)^a	39.7 (1.43)	40.5 (1.21)	0.06 (−1.4-0.03)
BW (kgs)^a	3.48 (0.7)	3.61 (0.61)	0.31 (−4.7–0.13)
Gender, male, n (%)^b	9 (76%)	14 (58%)	0.70
Mode of delivery n (%)^b
LSCS	7 (53)	11 (45)	0.70
SVD	3 (23)	7 (29)	0.73
Inst	3 (23)	6 (25)	0.73
Apgar @1 min^c	5 (3–6)	2 (1–5)	0.003
Apgar@5 mins^c	7 (5–8)	4 (2–7)	0.01
Apgar@10 mins^c	7.5 (6–9)	5 (3–7)	0.01
TH, n (%)^b	0 (0)	15 (62)	< 0.001
Seizures, n (%)^b	0 (0)	17 (70)	< 0.001
MRI- Abnormal, n (%)^b	0/0	13 (50)	< 0.001
ASQ -GM	56 (4)	48 (9)	0.03

GA gestational age, BW birth weight, SVD spontaneous vaginal delivery, inst. instrumental delivery, TH therapeutic hypothermia, ASQ ages and stages questionnaire, GM gross motor skill score. ^a For normally distributed data, mean ± SD is expressed, and the independent Student-t test was used for comparison, where p < 0.05 is significant with 95% confidence intervals (CI). ^b For binary variables, the χ2 test was used for comparison. ^c For skewed data, medians and IQRs are expressed and the Mann-Whitney U test was used for comparison

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