Fig. 2From: Homozygous NOTCH3 p.R587C mutation in Chinese patients with CADASIL: a case reportDNA Sequencing analysis of NOTCH3 in three family members with CADASIL. The homozygous NOTCH3 c.1759C > T (p.R587C) mutation in exon 11 was detected in the patient 1 and patient 2, while the same heterozygous mutation was detected in the son of patient 1Back to article page