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Table 2 Predictors for early death

From: Midbrain/pons area ratio and clinical features predict the prognosis of progressive Supranuclear palsy

 

Univariate

Multivariate

HR (95%CI)

P value

HR (95%CI)

P value

Gender (M/F)

1.314 (0.492–3.511)

0.581

  

Age at onset

0.999 (0.942–1.060)

0.970

2.087 (1.146–3.801)

0.016

phenotype (non-RS:RS)

0.417 (0.118–1.477)

0.417

  

Early falls

3.554 (1.012–12.485)

0.048

  

Early FOG

0.679 (0.238–1.932)

0.679

  

Early bulbar paralysis

4.391 (1.212–15.905)

0.024

  

Early apathy

3.040 (1.128–8.189)

0.028

  

Early incontinence

4.958(1.704–14.430)

0.003

  

MMSE

0.886 (0.755–1.040)

0.139

  

M/P area ratio (%) a

0.808 (0.697–0.937)

0.005

0.808 (0.697–0.937)

0.005

  1. a adjusted for age and interval from onset to brain MRI