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Table 1 Allelic frequencies of SNPs in patients with and without END

From: Variants in clopidogrel-relevant genes and early neurological deterioration in ischemic stroke patients receiving clopidogrel

 Patients with END
(n = 95)
Patients without END
(n = 280)
p value
CYP2C8 (rs17110453)
 AA43 (45.3)132 (47.1)0.751
 AC + CC52 (54.7)148 (52.9) 
CYP2C8 (rs1934980)
 CC15 (15.8)40 (14.3)0. 723
 CT + TT80 (84.2)240 (85.7) 
CYP2C9 (rs1799853)
 CC95 (100)280 (100)
CYP2C9 (rs1057910)
 AA85 (89.5)245 (87.5)0.626
 AC + CC10 (10.5)35 (12.5) 
CYP3A4(rs2242480)
 CC51 (53.7)155 (55.4)0.786
 TT + CT44 (46.3)125 (44.6) 
ABCB1(rs2032562)
 GG25 (26.3)65 (23.2)0.532
 TT + GT70 (73.7)215 (76.8) 
P2Y1(rs701265)
 AA46 (48.4)158 (56.4)0.193
 AG + GG49 (51.6)122 (43.6) 
P2Y1(rs1439010)
 AA48 (50.5)156 (55.7)0.402
 AG + GG47 (49.5)124 (44.3) 
P2Y1(rs1371097)
 CC45 (47.4)161 (57.5)0.096
 TT + CT50 (52.6)119 (42.5) 
CYP3A5(rs776746)
 AA12 (12.6)36 (12.9)0.998
 GG + AG83 (87.4)244 (87.1) 
CYP2C19(rs4244285)
 GG20 (16.8)133 (47.5)< 0.001
 AG + AA75 (78.9)147 (52.5) 
CYP2C19(rs4986893)
 GG86 (90.5)262 (93.6)0.752
 AG9 (9.5)18 (6.4) 
P2Y12(rs16863323)
 CC16 (16.8)62 (22.1)0.276
 TT + CT79 (83.2)218 (77.9) 
P2Y12(rs9859538)
 GG68 (71.6)206 (73.6)0.705
 AG + AA27 (28.4)74 (26.4) 
GPIIIa (rs2317676)
 AA62 (65.3)188 (67.1)0.724
 AG + GG33 (34.7)92 (32.9) 
GPIIIa (rs11871251)
 AA27 (28.4)86 (30.7)0.678
 AG + GG68 (71.6)194 (69.3) 
  1. SNPs single nucleotide polymorphisms; END, early neurological deterioration