Table 1 Allelic frequencies of SNPs in patients with and without END
Patients with END (n = 95) | Patients without END (n = 280) | p value | |
|---|---|---|---|
CYP2C8 (rs17110453) | |||
AA | 43 (45.3) | 132 (47.1) | 0.751 |
AC + CC | 52 (54.7) | 148 (52.9) | |
CYP2C8 (rs1934980) | |||
CC | 15 (15.8) | 40 (14.3) | 0. 723 |
CT + TT | 80 (84.2) | 240 (85.7) | |
CYP2C9 (rs1799853) | |||
CC | 95 (100) | 280 (100) | – |
CYP2C9 (rs1057910) | |||
AA | 85 (89.5) | 245 (87.5) | 0.626 |
AC + CC | 10 (10.5) | 35 (12.5) | |
CYP3A4(rs2242480) | |||
CC | 51 (53.7) | 155 (55.4) | 0.786 |
TT + CT | 44 (46.3) | 125 (44.6) | |
ABCB1(rs2032562) | |||
GG | 25 (26.3) | 65 (23.2) | 0.532 |
TT + GT | 70 (73.7) | 215 (76.8) | |
P2Y1(rs701265) | |||
AA | 46 (48.4) | 158 (56.4) | 0.193 |
AG + GG | 49 (51.6) | 122 (43.6) | |
P2Y1(rs1439010) | |||
AA | 48 (50.5) | 156 (55.7) | 0.402 |
AG + GG | 47 (49.5) | 124 (44.3) | |
P2Y1(rs1371097) | |||
CC | 45 (47.4) | 161 (57.5) | 0.096 |
TT + CT | 50 (52.6) | 119 (42.5) | |
CYP3A5(rs776746) | |||
AA | 12 (12.6) | 36 (12.9) | 0.998 |
GG + AG | 83 (87.4) | 244 (87.1) | |
CYP2C19(rs4244285) | |||
GG | 20 (16.8) | 133 (47.5) | < 0.001 |
AG + AA | 75 (78.9) | 147 (52.5) | |
CYP2C19(rs4986893) | |||
GG | 86 (90.5) | 262 (93.6) | 0.752 |
AG | 9 (9.5) | 18 (6.4) | |
P2Y12(rs16863323) | |||
CC | 16 (16.8) | 62 (22.1) | 0.276 |
TT + CT | 79 (83.2) | 218 (77.9) | |
P2Y12(rs9859538) | |||
GG | 68 (71.6) | 206 (73.6) | 0.705 |
AG + AA | 27 (28.4) | 74 (26.4) | |
GPIIIa (rs2317676) | |||
AA | 62 (65.3) | 188 (67.1) | 0.724 |
AG + GG | 33 (34.7) | 92 (32.9) | |
GPIIIa (rs11871251) | |||
AA | 27 (28.4) | 86 (30.7) | 0.678 |
AG + GG | 68 (71.6) | 194 (69.3) | |