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Table 2 Comparison of the best models, prediction accuracies, cross-validation consistencies, and P values for END identified by generalized multifactor dimensionality reduction analysis

From: Variants in clopidogrel-relevant genes and early neurological deterioration in ischemic stroke patients receiving clopidogrel

Best modela

Training balanced accuracy

Testing balanced accuracy

Cross-validation consistency

Sign test (P value)

16

0.613

0.582

7/10

6 (0.432)

1,2

0.418

0.534

8/10

8 (0.296)

1, 2, 3

0.612

0.623

10/10

9 (0.019)

1, 2, 3, 4

0.513

0.586

8/10

6 (0.632)

1, 2, 3, 4, 5

0.617

0.522

9/10

8 (0.763)

1, 2, 3, 4, 5, 6

0.543

0.514

7/10

7 (0.604)

1, 2, 3, 4, 5, 6, 7

0.476

0.495

6/10

5 (0.835)

1, 2, 3, 4, 5, 6, 7, 8

0.543

0.566

7/10

7 (0.351)

1, 2, 3, 4, 5, 6, 7, 8, 9

0.446

0.552

8/10

5 (0.675)

1, 2, 3, 4, 5, 6, 7, 8, 9, 10

0.612

0.624

6/10

6 (0.723)

1, 2, 3, 4, 5, 6, 7, 8, 9, 10,11

0.575

0.513

7/10

7 (0.372)

1, 2, 3, 4, 5, 6, 7, 8, 9, 10,11,12

0.484

0.497

5/10

6 (0.667)

1, 2,3, 4, 5, 6, 7, 8, 9, 10,11,12,13

0.597

0.583

7/10

5 (0.432)

1, 2, 3, 4, 5, 6, 7, 8, 9, 10,11,12,13,14

0.582

0.605

8/10

6 (0.317)

1, 2, 3, 4, 5, 6, 7, 8, 9, 10,11,12,13,14,15

0.622

0.572

6/10

8 (0.186)

1, 2, 3, 4, 5, 6, 7, 8, 9, 10,11,12,13,14,15,16

0.475

0.402

4/10

5 (0.726)

  1. END early neurological deterioration
  2. a Numbers 1–16 represent rs4244285, rs2317676, rs16863323, rs17110453, rs11871251, rs776746, rs1371097, rs701265, rs1439010, rs2242480, rs9859538, rs4986893, rs1934980, rs1799853, rs1057910, and rs2032562, respectively