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Table 2 Associations between chemokines and FXS diagnosis adjusted for age, BMI and time of sampling

From: Reduced serum levels of pro-inflammatory chemokines in fragile X syndrome

 

Dataset

Males + Females (N = 54)

Males (N = 44)

Covariates

 Age

0

0

 Time of sampling

0

−0.04093

 BMI

0

−0.15352

Chemokines

CCL2

−0.03703

−0.05208

 CCL3

−0.01263

0

 CCL4

0

0.06623

CCL11

−0.01220

−0.01161

 CCL13

0

−0.05315

 CCL17

0

−0.00101

CCL22

−0.00060

−0.00743

CCL26

−0.04703

−1.04540

CXCL10

−0.01051

−0.03173

  1. Coefficients were obtained using robust Elastic Net regression with 2000 subsampling steps on the whole dataset (males and females subjects: N = 54, n = 25 FXS patients, n = 29 controls) and in a dataset reduced to male subjects (N = 44, n = 20 FXS patients, n = 24 controls). Coefficients distinct from zero are shaded in grey and convergent associations across the two datasets are bolded