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Table 1 Baseline characteristics of patients according to eGRF

From: Influence of renal function on stroke outcome after mechanical thrombectomy: a prospective cohort study

 eGFR (ml/min/1.73 m2) 
≤44 (G3b–5)
n = 27
45–59 (G3a)
n = 46
60–89 (G2)
n = 170
≥90 (G1)
n = 130
p
Demographic
 Age, y82 (75–85)77 (66–83.3)76 (70–81)63.5 (55–70)< 0.001
 Male16 (59.3)30 (65.2)102 (60.0)87 (66.9)0.621
 Weight, Kg64 (60–70)65 (60–70)65 (60–70)65 (60–75)0.633
Cardiovascular risk factors
 Hypertension19 (70.4)39 (84.8)131 (77.1)82 (63.1)0.011
 Diabetes8 (29.6)10 (21.7)32 (18.8)24 (18.5)0.573
 Coronary artery disease8 (29.6)15 (32.6)46 (27.1)15 (11.5)0.002
 Atrial fibrillation14 (51.9)19 (41.3)69 (40.6)26 (20.0)< 0.001
 TIA/stroke5 (18.5)14 (30.4)51 (30.2)22 (16.9)0.04
 Smokinga6 (22.2)19 (41.3)50 (29.6)57 (43.8)0.026
Clinical features on admission
 NIHSS score16 (14–20)16.5 (11–24)16 (12–20)13.5 (9–18)0.005
 OTT, min202 (134–345)178 (136–309)195 (130–333)211 (155–379)0.352
 SBP, mmHg146 ± 22144 ± 21144 ± 24138 ± 230.127
 DBP, mmHg88 ± 1786 ± 1687 ± 1583 ± 150.149
 Prior tPA7 (25.9)21 (45.9)70 (41.2)61 (46.9)0.223
 TOAST classification
  Large artery atherosclerosis10 (37)18 (39.1)70 (41.2)72 (55.4)0.047
  Cardioembolism16 (59.3)25 (54.3)87 (51.2)46 (35.4)0.013
  Other1 (3.7)3 (6.5)13 (7.6)12 (9.2)0.875
 Occlusion site
  Anterior circulation23 (85.2)38 (82.6)138 (82.1)102 (79.1)0.826
  ICA/ICA terminal bifurcation8 (29.6)24 (52.2)56 (33.3)46 (35.7)0.102
  Middle cerebral artery15 (55.6)14 (30.4)82 (48.8)56 (43.4)0.099
  Posterior circulation4 (14.8)8 (17.4)30 (17.9)27 (20.9)0.848
  Basilar artery4 (14.8)5 (10.9)14 (8.3)16 (12.4)0.348
  Vertebral artery02 (4.3)15 (8.9)10 (7.8)0.404
  Posterior cerebral artery01 (2.2)1 (0.5)1 (0.8)0.618
Laboratory tests
 Platelet count, 10^9/L158 (137–232)171 (143–220)174.5 (141–223)189 (144–231)0.446
 PT/INR1.04 (0.99–1.10)1.02 (0.99–1.07)1.01 (0.96–1.08)0.99 (0.95–1.06)0.034
 Glucose, mmol/L7.0 (5.8–9.4)7.0 (5.6–8.2)6.5 (5.4–8.0)6.2 (5.1–7.5)0.027
 Glycosylated hemoglobin, %5.8 (5.7–6.8)6.2 (5.6–6.9)5.9 (5.5–6.4)5.8 (5.5–6.3)0.284
 Total cholesterol, mmol/L3.54 (2.98–4.85)3.77 (3.32–4.78)4.14 (3.51–4.87)4.35 (3.59–5.14)0.025
 LDL, mmol/L2.21 (1.78–2.85)2.29 (1.73–3.07)2.43 (1.92–3.06)2.70 (2.12–3.24)0.037
 HDL, mmol/L1.13 ± 0.331.13 ± 0.301.12 ± 0.271.16 ± 0.310.667
 Triglyceride, mmol/L0.9 (0.75–1.85)1.02 (0.73–1.61)1.04 (0.76–1.47)1.09 (0.75–1.57)0.843
 Urea nitrogen, mmol/L9.64 (7.45–12.10)7.50 (5.41–8.95)5.93 (4.81–7.21)4.70 (4.09–5.54)< 0.001
 Homocysteine, umol/L14.45 (12.00–17.88)14.66 (12.14–18.33)13.01 (10.89–16.78)11.51 (9.76–13.91)< 0.001
  1. TIA transient ischemic attack, NIHSS National Institutes of Health Stroke Scale, OTT, onset to treatment time, SBP systolic blood pressure, DBP diastolic blood pressure, tPA tissue plasminogen activator, ICA internal carotid artery, PT/INR prothrombin time and international normalized ratio, LDL low density lipoprotein, HDL high density lipoprotein
  2. aSmoking status including both former and current