TY - JOUR AU - Oorschot, Sander AU - Brehm, Merel A. AU - van Groenestijn, Annerieke C. AU - Koopman, Fieke S. AU - Verhamme, Camiel AU - Eftimov, Filip AU - Jelsma, Judith G. M. AU - Jorstad, Harald T. AU - Nollet, Frans AU - Voorn, Eric L. PY - 2020 DA - 2020/05/13 TI - Efficacy of a physical activity programme combining individualized aerobic exercise and coaching to improve physical fitness in neuromuscular diseases (I’M FINE): study protocol of a randomized controlled trial JO - BMC Neurology SP - 184 VL - 20 IS - 1 AB - In individuals with neuromuscular diseases (NMD), symptoms of muscle weakness, fatigue and pain may limit physical activity. Inactivity leads to reduced physical fitness, which further complicates daily life functioning. Due to inconclusive evidence regarding exercise in NMD, the optimal training approach and strategies to preserve an active lifestyle remain to be determined. The physical activity programme I’M FINE, consisting of individualized aerobic exercise to improve physical fitness and coaching to preserve an active lifestyle, was therefore developed. The primary objective of this study will be to evaluate the efficacy of the I’M FINE programme in terms of improved physical fitness in individuals with slowly progressive NMD, compared to usual care. SN - 1471-2377 UR - https://doi.org/10.1186/s12883-020-01725-0 DO - 10.1186/s12883-020-01725-0 ID - Oorschot2020 ER -