Table 3 An overview of the study time schedule for assessments and interventions
Timepoint | T0 | T1 | T1.5 | T2 | T3 |
|---|---|---|---|---|---|
Screening: | |||||
- Modified Telephone Interview for Cognitive Status (TICS-m) | X | ||||
- MRI safety screening | X | ||||
- Medical Health History (MHH) | X | ||||
- Questions from ACSM guidelines for determining risk of physical activity | X | ||||
- Alzheimer’s family history questionnaire (REVEAL) | X | ||||
- Center for Epidemiological Studies Depression Scale Revised (CESD-R) | X | ||||
- Everyday Cognition Questionnaire (ECOG) | X | ||||
- Community Healthy Activities Model Program for Seniors (CHAMPS) | X | ||||
- Pittsburgh Sleep Quality Index | X | ||||
Enrollment | |||||
- Montreal Cognitive Assessment (MoCA) | X | ||||
- Informed consent | X | ||||
Allocation | X | ||||
Interventions: | |||||
- Physical activity | ←———————————→ | ||||
- Usual care | ←———————————→ | ||||
Assessments: | |||||
- Cognitive tests | X | X | X | ||
- Neuroimaging | X | X | |||
- Blood sample collection | X | X | |||
- Resting heart rate assessment | X | X | X | ||
- Submaximal exercise test | X | X | X | ||