The effect of physical activity on cognition relative to APOE genotype (PAAD-2): study protocol for a phase II randomized control trial

Table 4 Magnetic Resonance Imaging Sequences

Sequence	Parameters
T1-weighted MP-RAGE	Resolution = 1.0 × 1.0 × 1.0 mm, TR = 2300 ms, TE = 2.26 ms, TI = 900 ms, FoV = 256 mm, 192 slices
T2-FLAIR	Resolution = 1.0 × 1.0 × 1.0 mm, TR = 5000 ms, TE = 381 ms, TI = 1800 ms, FoV = 256 mm, 192 slices
Resting-state fMRI	Resolution = 3.4 × 3.4 × 3.4 mm, TR = 3000 ms, TE = 30 ms, FoV = 220 mm, 48 slices, EPI factor = 64, 200 measurements
Famous Name Task fMRI (performed twice)	Resolution = 3.4 × 3.4 × 3.4 mm, TR = 3000 ms, TE = 30 ms, FoV = 220 mm, 48 slices, EPI factor = 64, 111 measurements
High resolution Hippocampus	Resolution = 0.4 × 0.4 × 2.0 mm, TR = 8020 ms, TE = 52 ms, FoV = 175 mm aligned perpendicular to the hippocampus, 29 slices
Diffusion weighted acquisition	Resolution = 2.0 × 2.0 × 2.0 mm, TR = 11,000 ms, TE = 97 ms, FoV = 256 mm, 80 slices, 30 diffusion directions

MP-RAGE Magnetization Prepared-RApid Gradient Echo, TR repetition time, TE echo time, TI inversion time, FoV Field of View, FLAIR Fluid-Attenuated Inversion Recovery, fMRI functional Magnetic Resonance Imaging

ISSN: 1471-2377