Fig. 5

ICA correlation with severity of neural damage, as measured by serum NfL. Each scatter plot shows the NfL level in serum (y axis) vs. ICA or SDMT (x axis). Each blue dot indicates an individual; the blue dashed lines are results of linear regression, fitting a linear line to the data in each plot. For each plot, the Pearson correlation between NfL level and the reference cognitive test is written in the bottom-left. Stars (*) show significant correlations at p < 10^− 6