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Table 1 Demographics of the patients with MSA, SCA3, and the controls

From: Vertical pons hyperintensity and hot cross bun sign in cerebellar-type multiple system atrophy and spinocerebellar ataxia type 3

 Sex Distributiona
(Male/Female)
Age at MRIb
(years, median, range)
Age at Onsetc
(years, mean±SD)
Disease Durationd
(years, median, range)
Frequency of MRIb
(times, median, range)
MSA (n = 80)40/4067.0 (46-82)63.2 ± 8.72.2 (0.2-8.3)1 (1-5)
MSA-C (n = 41)21/2063.5 (46-82)61.3 ± 9.92.1 (0.2-8.3)1 (1-5)
SCA3 (n = 26)10/1658.5 (24-82)46.0 ± 17.26.7 (0.8-24.0)1 (1-6)
Controls (n = 22)11/1164.0 (42-82)NANA1 (1-1)
P value for MSA vs. SCA3NANA<0.001<0.001NA
P value for MSA-C vs. SCA3NANA<0.001<0.001NA
P value for group comparison
(MSA, SCA3, Controls)
0.5750.01NANA0.002
P value for group comparison
(MSA-C, SCA3, Controls)
0.5680.107NANA0.003
P value for post-hoc group comparisons
 MSA vs. SCA3NA0.003NANA0.597
 MSA vs. ControlsNA0.235NANA<0.001
 SCA3 vs. ControlsNA0.191NANA0.001
 MSA-C vs. SCA3NANANANA0.713
 MSA-C vs. ControlsNANANANA0.001
  1. aChi-squared test (post-hoc chi-squared tests adjusted for multiple comparison: P < 0.05/3 = 0.0167)
  2. bNonparametric test (Kruskal-Wallis 1-way ANOVA with post-hoc Mann-Whitney U test adjusted for multiple comparison: P < 0.05/3 = 0.0167)
  3. cStudent's t-test
  4. dMann-Whitney U test