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Fig. 1 | BMC Neurology

Fig. 1

From: Spinal metastasis of glioblastoma multiforme before gliosarcomatous transformation: a case report

Fig. 1

Brain magnetic resonance imaging (MRI) results for glioblastoma multiforme (GBM) that recurred at the same location as gliosarcoma (GS) after treatment. Initial T1-weighted (a) and postcontrast T1 FLAIR (b) brain MRI results obtained at the emergency department, demonstrating a large cystic mass with surrounding perifocal edema. T1-weighted (c) and postcontrast T1 FLAIR (d) and cerebral blood flow (CBF) (e) in the brain MRI after proton beam therapy, revealing mild interval enlargement of the right parietotemporal GBM with perifocal edema. T1-weighted (f) and postcontrast T1 FLAIR (g) and CBF (h) brain MRI after targeted therapy with bevacizumab, illustrating mild recurrence and avascular necrosis. Axial T1-weighted (h) and postcontrast T1 FLAIR (i) and CBF (j) image of secondary gliosarcoma. MRI revealed obvious tumor recurrence along the surgical margin. Tumor seeding was noted in the fourth ventricle, causing obstructive hydrocephalus and midbrain compression. The CBF indicated avascular necrosis

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