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Fig. 4 | BMC Neurology

Fig. 4

From: Spinal metastasis of glioblastoma multiforme before gliosarcomatous transformation: a case report

Fig. 4

Gliosarcoma images. a Gliomatous component: hematoxylin and eosin staining (a1), glial fibrillary acidic protein (GFAP) positivity (a2), Ki-67 index (nearly 40%) (a3), vimentin negativity (a4), silver staining negativity (a5), and phosphatase and tensin homolo (PTEN) positivity (a6). b Sarcomatous component: hematoxylin and eosin staining (original magnification, 200×; b1), GFAP negativity (b2), diffuse staining with MIB-1 antibody (Ki-67 index > 50%) in tumor cells (i.e., abundant proliferative process), (b3), vimentin positivity (b4), silver staining positivity (b5), and PTEN negativity (b6). Magnification, × 200. (PTEN: phosphatase and tensin homolog)

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