Skip to main content

Table 5 Overview of assessments at different test-sessions

From: Study protocol: improving cognition in people with progressive multiple sclerosis: a multi-arm, randomized, blinded, sham-controlled trial of cognitive rehabilitation and aerobic exercise (COGEx)

Outcome

Initial Screening

In person Screening

Baseline Assessment

12-week intervention

Immediate Post 12-week Assessment

3-months follow-up Interview

6-months follow-up Assessment

Cognitive

 BICAMS*

SDMT

 

X

  

X

 

X

  Token Test

 

X

     

 BICAMS*

  CVLT

  

X

 

X

 

X

 BICAMS*

  BVMT-R

  

X

 

X

 

X

  WTAR or NART

  

X

    

Physical

 Visual Acuity test

 

X

     

 ActiGraph Device

 

X

 

X**

   

 CMI

  

X

 

X

 

X

 6MWT

  

X

 

X

 

X

 IET

  

X

 

X

 

X

 Functional MRI***

  

X

 

X

 

X

PRO´s

 Fitness Questionnaire****

X

      

 GLTEQ

X

      

 Demographic form

 

X

     

 BDI-II

 

X

     

 FAMS

  

X

 

X

 

X

 EQ-5D-5L

  

X

 

X

 

X

 MSIS-29-V2

  

X

 

X

 

X

 MSWS-12

  

X

 

X

 

X

 PDQ-20

  

X

 

X

 

X

 MFIS

  

X

 

X

 

X

 HADS

  

X

 

X

 

X

Customized

 Phone Interview

X

      

 Consent form

 

X

     

 Medication list

 

X

  

X

 

X

 Goal Setting Sheet

   

X

   

 Adverse Event form*****

   

X

   

 Post Intervention Interview

     

X

 

 Post Intervention Survey

      

X

 Serious Adverse Event form*****

      

X

  1. *Available in three parallel versions;** measured during the week following the intervention; ***only performed at 3 sites; **** AHA/ACSM Health/Fitness Facility Pre participation Screening Questionnaire *****only completed if necessary
  2. Abbreviations: BICAMS Brief International Cognitive Assessment for MS, SDMT Symbol Digit Modalities Test, CVLT California Verbal Learning Test, BVMT-R Brief Visuospatial Memory Test-Revised, WTAR Wechsler Test of Adult Reading, NART National Adult Reading Test, CMI Cognitive-Motor Interference, 6MWT Six Minute Walk Test, IET Incremental Exercise Test, Functional MRI Functional Magnetic Resonance Imaging, GLTEQ Godin Leisure-Time Exercise Questionnaire, BDI-II Beck Depression Inventory-II, FAMS Functional Assessment of Multiple Sclerosis, EQ-5D-5L European Quality of Life-5 Dimensions, MSIS-29 V2 Multiple Sclerosis Impact Scale-29 Items Version2, MSWS-12 Multiple Sclerosis Walking Scale 12 Items, PDQ-20 Perceived Deficits Questionnaire 20 Items, MFIS Modified Fatigue Impact Scale, HADS Hospital Anxiety and Depression Scale