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Table 1 Comparison of clinical characteristics between the exposed group with CMV disease and the matched unexposed group without CMV diseases

From: Association between cytomegalovirus end-organ diseases and moderate-to-severe dementia: a population-based cohort study

Characteristics

CMV diseases

P-value

No

Yes

(n = 3435)

(n = 687)

Sex, male

1950 (56.77)

390 (56.77)

>  0.999

Age, years

57.98 ± 11.41

57.98 ± 11.42

>  0.999

 ≥ 60 years

1405 (40.9)

281 (40.9)

>  0.999

Duration of total follow-up, years

4.10 ± 1.58

3.73 ± 1.80

<  0.001

Low income statusa

824 (23.99)

181 (26.35)

0.189

BMI, kg/m2

23.39 ± 5.95

22.63 ± 6.72

0.318

 ≥ 25 kg/m2

832 (24.22)

163 (23.73)

0.294

Co-morbid diseases, yesb

192 (5.59)

258 (37.55)

<  0.001

Solid organ transplant recipients

30 (0.87)

146 (21.25)

<  0.001

 Kidney

27 (0.79)

109 (15.87)

<  0.001

 Liver

3 (0.09)

19 (2.77)

<  0.001

 Heart

0 (0)

13 (1.89)

 Lung

0 (0)

5 (0.73)

HSCT recipients

16 (0.47)

95 (13.83)

<  0.001

Malignant neoplasmsc

113 (3.29)

69 (10.04)

<  0.001

End-stage renal disease on dialysis

92 (2.68)

35 (5.09)

<  0.001

NIDDM

386 (11.24)

205 (29.84)

<  0.001

Hypertension

974 (28.36)

328 (47.74)

<  0.001

Dyslipidaemia

607 (17.67)

201 (29.26)

<  0.001

Moderate-to-severe dementia

 All

105 (3.06)

38 (5.53)

0.001

 Alzheimer’s

77 (2.24)

23 (3.35)

0.085

 Vascular

12 (0.35)

7 (1.02)

0.018

 Other

16 (0.47)

8 (1.16)

0.028

  1. Data are expressed as number (percentage) and median ± standard deviation
  2. Abbreviations: BMI body mass index, CMV cytomegalovirus, ESRD end-stage renal disease, HSCT haematopoietic stem cell transplantation, NIDDM non-insulin-dependent diabetes mellitus, SOT solid organ transplantation
  3. aLower 25th percentile of socioeconomic status
  4. bPatients with ≥ one among co-morbid diseases of SOT recipients, HSCT recipients, malignant neoplasms, and ESRD on dialysis
  5. cIncluding haematologic malignancies and excluding in situ neoplasms