Skip to main content

Table 1 Comparison of clinical characteristics between the exposed group with CMV disease and the matched unexposed group without CMV diseases

From: Association between cytomegalovirus end-organ diseases and moderate-to-severe dementia: a population-based cohort study

CharacteristicsCMV diseasesP-value
NoYes
(n = 3435)(n = 687)
Sex, male1950 (56.77)390 (56.77)>  0.999
Age, years57.98 ± 11.4157.98 ± 11.42>  0.999
 ≥ 60 years1405 (40.9)281 (40.9)>  0.999
Duration of total follow-up, years4.10 ± 1.583.73 ± 1.80<  0.001
Low income statusa824 (23.99)181 (26.35)0.189
BMI, kg/m223.39 ± 5.9522.63 ± 6.720.318
 ≥ 25 kg/m2832 (24.22)163 (23.73)0.294
Co-morbid diseases, yesb192 (5.59)258 (37.55)<  0.001
Solid organ transplant recipients30 (0.87)146 (21.25)<  0.001
 Kidney27 (0.79)109 (15.87)<  0.001
 Liver3 (0.09)19 (2.77)<  0.001
 Heart0 (0)13 (1.89)
 Lung0 (0)5 (0.73)
HSCT recipients16 (0.47)95 (13.83)<  0.001
Malignant neoplasmsc113 (3.29)69 (10.04)<  0.001
End-stage renal disease on dialysis92 (2.68)35 (5.09)<  0.001
NIDDM386 (11.24)205 (29.84)<  0.001
Hypertension974 (28.36)328 (47.74)<  0.001
Dyslipidaemia607 (17.67)201 (29.26)<  0.001
Moderate-to-severe dementia
 All105 (3.06)38 (5.53)0.001
 Alzheimer’s77 (2.24)23 (3.35)0.085
 Vascular12 (0.35)7 (1.02)0.018
 Other16 (0.47)8 (1.16)0.028
  1. Data are expressed as number (percentage) and median ± standard deviation
  2. Abbreviations: BMI body mass index, CMV cytomegalovirus, ESRD end-stage renal disease, HSCT haematopoietic stem cell transplantation, NIDDM non-insulin-dependent diabetes mellitus, SOT solid organ transplantation
  3. aLower 25th percentile of socioeconomic status
  4. bPatients with ≥ one among co-morbid diseases of SOT recipients, HSCT recipients, malignant neoplasms, and ESRD on dialysis
  5. cIncluding haematologic malignancies and excluding in situ neoplasms