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Table 1 Comparison of clinical characteristics between the exposed group with CMV disease and the matched unexposed group without CMV diseases

From: Association between cytomegalovirus end-organ diseases and moderate-to-severe dementia: a population-based cohort study

Characteristics CMV diseases P-value
No Yes
(n = 3435) (n = 687)
Sex, male 1950 (56.77) 390 (56.77) >  0.999
Age, years 57.98 ± 11.41 57.98 ± 11.42 >  0.999
 ≥ 60 years 1405 (40.9) 281 (40.9) >  0.999
Duration of total follow-up, years 4.10 ± 1.58 3.73 ± 1.80 <  0.001
Low income statusa 824 (23.99) 181 (26.35) 0.189
BMI, kg/m2 23.39 ± 5.95 22.63 ± 6.72 0.318
 ≥ 25 kg/m2 832 (24.22) 163 (23.73) 0.294
Co-morbid diseases, yesb 192 (5.59) 258 (37.55) <  0.001
Solid organ transplant recipients 30 (0.87) 146 (21.25) <  0.001
 Kidney 27 (0.79) 109 (15.87) <  0.001
 Liver 3 (0.09) 19 (2.77) <  0.001
 Heart 0 (0) 13 (1.89)
 Lung 0 (0) 5 (0.73)
HSCT recipients 16 (0.47) 95 (13.83) <  0.001
Malignant neoplasmsc 113 (3.29) 69 (10.04) <  0.001
End-stage renal disease on dialysis 92 (2.68) 35 (5.09) <  0.001
NIDDM 386 (11.24) 205 (29.84) <  0.001
Hypertension 974 (28.36) 328 (47.74) <  0.001
Dyslipidaemia 607 (17.67) 201 (29.26) <  0.001
Moderate-to-severe dementia
 All 105 (3.06) 38 (5.53) 0.001
 Alzheimer’s 77 (2.24) 23 (3.35) 0.085
 Vascular 12 (0.35) 7 (1.02) 0.018
 Other 16 (0.47) 8 (1.16) 0.028
  1. Data are expressed as number (percentage) and median ± standard deviation
  2. Abbreviations: BMI body mass index, CMV cytomegalovirus, ESRD end-stage renal disease, HSCT haematopoietic stem cell transplantation, NIDDM non-insulin-dependent diabetes mellitus, SOT solid organ transplantation
  3. aLower 25th percentile of socioeconomic status
  4. bPatients with ≥ one among co-morbid diseases of SOT recipients, HSCT recipients, malignant neoplasms, and ESRD on dialysis
  5. cIncluding haematologic malignancies and excluding in situ neoplasms