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Table 2 Regional 123I-FP-CIT uptake values for the PD and Control groups

From: Extrastriatal 123I-FP-CIT SPECT impairment in Parkinson’s disease – the PPMI cohort

  PD (n = 154) Controls (n = 62) pval
Caudate nucleus 2.66 ± 0.95 3.60 ± 1.03 <  0.0001
Putamen 1.34 ± 0.46 2.54 ± 0.44 < 0.0001
Pallidum 1.51 ± 0.80 2.56 ± 0.56 < 0.0001
Insula 0.43 ± 0.16 0.64 ± 0.19 < 0.0001
Amygdala 0.52 ± 0.21 0.59 ± 0.19 0.01
  1. Average (mean of left and right) 123I-FP-CIT uptake values for PD and Control groups for striatal and extrastriatal regions-of-interest. For comparative purposes, the same reference region (occipital lobe) was used for the present results. All group comparisons are performed using Mann-Whitney U test