Amino acid metabolism, lipid metabolism, and oxidative stress are associated with post-stroke depression: a metabonomics study

Table 3 Differential metabolites between the post-stroke depression and control groups

#	Compounds	RT	M/Z	VIP (OPLS-DA)	P (t-test)	log₂_FC
1	α-N-Phenylacetyl-L-glutamine	202.24	265	2.11	0.028	1.37
2	IS	233.88	200	2.63	0.048	0.21
3	DHA	36.67	327.23	1.47	0.011	0.77
4	Betaine	286.68	118.08	1.43	0.043	−0.79
5	Palmitic acid	73.98	274.27	6.35	0.001	−0.51
6	MHPG-SO₄	32.31	282.28	2.98	0.045	−2.37

Log₂FC is the logarithm of the mean ratio between the stroke group and post-stroke depression group. Positive numbers represent increase in the post-stroke depression group compared with the control group, and negative numbers mean a decrease

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