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Table 3 Crude and adjusted odds or hazard ratio for hospital mortality (logistic regression and Cox-proportional hazards) in patients with different platelet count categories

From: Thrombocytopenia and platelet course on hospital mortality in neurological intensive care unit: a retrospective observational study from large database

CategoriesLogistic Regression AnalysisCox Proportional Hazards Model
OR (95% CI)P valueHR (95% CI)P value
Platelet count at admission
Crude
 NTP at admission1 [Reference] 1 [Reference] 
 TP at admission1.45 (1.2–1.75)0.0021.32 (1.11–1.57)0.002
Model 1
 NTP at admission1 [Reference] 1 [Reference] 
 TP at admission1.02 (0.83–1.26)0.8191.03 (0.86–1.24)0.715
Model 2
 NTP at admission1 [Reference] 1 [Reference] 
 TP at admission1.14 (0.92–1.41)0.2371.15 (0.95–1.38)0.143
Platelet course during NICU stay
Crude
 Group 4 (NTP-NTP)1 [Reference] 1 [Reference] 
 Group 1 (TP-TP)2.63 (2.1–3.27)< 0.0011.27 (1.11–1.44)< 0.001
 Group 2 (TP-NTP)0.98 (0.78–1.25)0.8971.03 (0.89–1.19)0.711
 Group 3 (NTP-TP)2.79 (2.27–3.42)< 0.0011.32 (1.15–1.53)< 0.001
Model 1
 Group 4 (NTP-NTP)1 [Reference] 1 [Reference] 
 Group 1 (TP-TP)1.73 (1.35–2.21)< 0.0011.97 (1.59–1.44)< 0.001
 Group 2 (TP-NTP)0.63 (0.44–0.89)0.0110.47 (0.34–0.66)< 0.001
 Group 3 (NTP-TP)1.82 (1.45–2.27)< 0.0011.22 (1.00–1.48)0.052
Model 2
 Group 4 (NTP-NTP)1 [Reference] 1 [Reference] 
 Group 1 (TP-TP)2.05 (1.57–2.66)< 0.0012.37 (1.89–2.98)< 0.001
 Group 2 (TP-NTP)0.65 (0.48–0.93)0.0210.49 (0.35–0.68)< 0.001
 Group 3 (NTP-TP)1.65 (1.30–2.09)< 0.0011.08 (0.88–1.33)0.438
  1. Model 1used Acute Physiology and Chronic Health Evaluation IV score as covariate
  2. Model 2 used Acute Physiology and Chronic Health Evaluation IV score, admission diagnosis, whether the patient had heart failure, hypertension, cancer, chronic renal insufficiency, cirrhosis, use of mechanical ventilation, vasopressors, mannitol, hypertonic saline, heparin, glucocorticoid, red blood cell transfusion and platelet transfusion as covariates
  3. OR Odd ratio, CI Confidential interval, HR Hazard ratio, TP Thrombocytopenia, NTP Non thrombocytopenia, NICU Neurological intensive care unit