From: Clinical features of Guillain–Barré syndrome patients with elevated serum creatine kinase levels
GBS patients with elevated CK levels (n = 14) | GBS patients with normal CK levels (n = 37) | P-value | |
---|---|---|---|
Age, years, mean ± SD | 41.2 ± 10.2 | 47.7 ± 21.1 | NS |
Males, n (%) | 12 (86) | 19 (51) | 0.029 |
Antecedent infection, n (%) | 13 (93) | 22 (59) | 0.039 |
Gastroenteritis, n (%) | 5 (35) | 14 (38) | NS |
Upper respiratory tract infection, n (%) | 8 (57) | 8 (21) | 0.021 |
Clinical symptoms | |||
Hypoesthesia, n (%) | 1 (7) | 15 (41) | 0.039 |
Cranial nerve involvement, n (%) | 2 (14) | 19 (51) | 0.025 |
Ophthalmoparesis | 1 (7) | 7 (19) | NS |
Facial palsy | 1 (7) | 10 (27) | NS |
Oropharyngeal palsy | 2 (14) | 17 (46) | NS |
Urinary retention, n (%) | 0 (0) | 12 (32) | 0.022 |
Preserved tendon reflexes, n (%) | 9 (64) | 16 (43) | NS |
Anti-GM1 antibody, n (%) | 8/12 (67) | 8/32 (25) | 0.016 |
Hughes grade at peak | NS | ||
1 | 1 (7) | 3 (8) | |
2 | 7 (50) | 13 (35) | |
3 | 2 (14) | 4 (11) | |
4 | 3 (21) | 13 (35) | |
5 | 1 (7) | 3 (8) | |
6 | 0 (0) | 1 (3) |