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Table 1 Clinical and laboratory features of 51 patients with GBS

From: Clinical features of Guillain–Barré syndrome patients with elevated serum creatine kinase levels

 

GBS patients with elevated CK levels

(n = 14)

GBS patients with normal CK levels

(n = 37)

P-value

Age, years, mean ± SD

41.2 ± 10.2

47.7 ± 21.1

NS

Males, n (%)

12 (86)

19 (51)

0.029

Antecedent infection, n (%)

13 (93)

22 (59)

0.039

 Gastroenteritis, n (%)

5 (35)

14 (38)

NS

 Upper respiratory tract infection, n (%)

8 (57)

8 (21)

0.021

Clinical symptoms

 Hypoesthesia, n (%)

1 (7)

15 (41)

0.039

 Cranial nerve involvement, n (%)

2 (14)

19 (51)

0.025

  Ophthalmoparesis

1 (7)

7 (19)

NS

  Facial palsy

1 (7)

10 (27)

NS

  Oropharyngeal palsy

2 (14)

17 (46)

NS

 Urinary retention, n (%)

0 (0)

12 (32)

0.022

 Preserved tendon reflexes, n (%)

9 (64)

16 (43)

NS

Anti-GM1 antibody, n (%)

8/12 (67)

8/32 (25)

0.016

Hughes grade at peak

NS

 1

1 (7)

3 (8)

 

 2

7 (50)

13 (35)

 

 3

2 (14)

4 (11)

 

 4

3 (21)

13 (35)

 

 5

1 (7)

3 (8)

 

 6

0 (0)

1 (3)

 
  1. Abbreviations: GBS Guillain–Barré syndrome, CK Creatine kinase, NS Not significant