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Fig. 3 | BMC Neurology

Fig. 3

From: DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study

Fig. 3

The rCBF change in the ipsilateral MCA after therapy in two patients with carotid artery stenosis shown by MRA. The upper figures showed a patient in NBP group. a MRA image showed that the patient had a severe stenosis in the left MCA (white arrow). b SPECT image showed that the rCBF in the ipsilateral MCA territory (8–11 ROIs) was impaired before treatment (decreased tracer uptake compared to mirror). c SPECT image showed that the decreased rCBF became improved after treatment (increased tracer uptake compared to B). The lower figures showed a patient in placebo group. d MRA image showed that the patient had a severe stenosis in the right MCA (white arrow). e SPECT image showed that the rCBF in the ipsilateral MCA territory (2–5 ROIs) was impaired before treatment (decreased tracer uptake compared to mirror). f SPECT image showed that the decreased rCBF became further deteriorated after treatment (decreased tracer uptake compared to e). CBF, cerebral blood flow; rCBF, regional CBF; MCA, middle cerebral artery; MRA, magnetic resonance angiography; NBP, Dl-3-butylphthalide; SPECT, single photon emission computed tomography; ROI, regions of interest

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BMC Neurology

ISSN: 1471-2377

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