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Table 4 Comparisons of whole CBF outcomes in ipsilateral MCA territory of carotid artery system stenosis between NBP and placebo groups stratified by stenotic degree

From: DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study

whole CBF outcomesSevere stenosis (n = 75)Occlusion (n = 19)
NBPplaceboP valuesNBPplaceboP values
Deterioration
n (%)
1 (2.9%)11 (27.5%)0.0090 (0%)1 (16.7%)0.037
Stabilization
n (%)
29 (82.9%)22 (55.0%)8 (61.5%)5 (83.3%)
Amelioration
n (%)
5 (14.3%)7 (17.5%)5 (38.5%)0 (0%)
  1. CBF cerebral blood flow, MCA middle cerebral artery, NBP Dl-3-butylphthalide; The whole CBF amelioration/deterioration was defined as the numbers of ROIs with rCBF amelioration/deterioration in the patients ≥2