Skip to main content

Table 4 Comparisons of whole CBF outcomes in ipsilateral MCA territory of carotid artery system stenosis between NBP and placebo groups stratified by stenotic degree

From: DL-3-n-butylphthalide improves cerebral hypoperfusion in patients with large cerebral atherosclerotic stenosis: a single-center, randomized, double-blind, placebo-controlled study

whole CBF outcomes

Severe stenosis (n = 75)

Occlusion (n = 19)

NBP

placebo

P values

NBP

placebo

P values

Deterioration

n (%)

1 (2.9%)

11 (27.5%)

0.009

0 (0%)

1 (16.7%)

0.037

Stabilization

n (%)

29 (82.9%)

22 (55.0%)

8 (61.5%)

5 (83.3%)

Amelioration

n (%)

5 (14.3%)

7 (17.5%)

5 (38.5%)

0 (0%)

  1. CBF cerebral blood flow, MCA middle cerebral artery, NBP Dl-3-butylphthalide; The whole CBF amelioration/deterioration was defined as the numbers of ROIs with rCBF amelioration/deterioration in the patients ≥2