Table 1 Comparison between MG relapsers and non-relapsers
From: Prospective study of stress, depression and personality in myasthenia gravis relapses
Variable | Total (n = 155) | Non-relapsers (n = 122) | Relapsers (n = 33) | p value |
|---|---|---|---|---|
Age (y) | 58.5 ± 14.0 | 58.5 ± 14.5 | 58.7 ± 12.3 | 0.9 |
Sex F | 80 (51.6) | 64 (52.5) | 16 (48.5) | 0.7 |
Disease duration (y) | 10.7 ± 8.8 | 10.7 ± 8.6 | 10.8 ± 9.6 | 1.0 |
Age of onset (y) | 47.8 ± 15.7 | 47.8 ± 16.2 | 47.9 ± 14.1 | 1.0 |
Generalized | 128 (82.6) | 97 (79.5) | 31 (93.9) | 0.05 |
MGII Score | 1.4 ± 8.4 | −1.6 ± 5.3 | 12.2 ± 7.7 | < 0.0001 |
Thymoma | 42 (27.1) | 33 (27.0) | 9 (27.3) | 1.0 |
Thymectomy | 87 (56.1) | 67 (54.9) | 20 (60.0) | 0.6 |
AchRAb | 64 (57.7) | 53 (60.2) | 11 (47.8) | 0.2 |
MuSK Ab | 6 (5.4) | 4 (4.5) | 2 (8.7) | 0.5 |
TICS-S | −5.8 ± 16.8 | −6.8 ± 16.4 | −1.8 ± 17.9 | 0.12 |
BDI-II | −0.4 ± 5.3 | −1.0 ± 5.2 | 1.7 ± 5.5 | 0.01 |
Potential triggers | 67 (43.2) | 52 (42.6) | 15 (45.5) | 0.8 |
Personal problems | 26 (16.7) | 17 (13.9) | 9 (27.3) | 0.07 |
Other illnesses | 48 (31.0) | 35 (28.7) | 13 (39.4) | 0.2 |
Medications (baseline) | ||||
Prednisone | 97 (63) | 75 (61) | 22 (67) | 0.59 |
Prednisone dose/day (mg) | 13.8 ± 9.7 | 12.7 ± 8.3 | 17.2 ± 13.2 | 0.15 |
Azathioprine | 56 (41) | 48 (40) | 8 (24) | 0.10 |
Mycophenolate | 26 (17) | 22 (18) | 4 (12) | 0.40 |
Reduction in Immunosuppressant (baseline to follow up) | 48 (31) | 40 (33) | 8 (24) | 0.32 |