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Fig. 3 | BMC Neurology

Fig. 3

From: Late-onset MELAS syndrome with mtDNA 14453G→A mutation masquerading as an acute encephalitis: a case report

Fig. 3

MR spectroscopy and 123I-IMP SPECT findings. Magnetic resonance spectroscopy (MRS, A) revealed a markedly elevated lactate concentration, which was detected as an inverted double peak (arrow) in the regions of interest on the high-intensity area within the right parietal lesion; a normal N-acetyl aspartate (NAA) level was also observed. On three-dimensional stereotactic surface projection (3D-SSP) analysis of 123I-IMP single photon emission tomography (SPECT, B), regional cerebral blood flow (rCBF) was compared with the blood flow of the normal control group using a Z test. Color-coding represents the statistical significance (Z score) of the increase in rCBF. Z score maps of the brain surface and tomographic views demonstrated that rCBF in the right temporo-occipital area was remarkably increased

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