Table 2 Characteristics of the patients according to D-dimer level
Abnormal D-dimer (n = 77) | Normal D-dimer (n = 206) | p-value | |
|---|---|---|---|
Age (years) | 68 ± 12 | 68 ± 11 | 0.683 |
Male | 50 (64.9%) | 122 (59.2%) | 0.381 |
Hypertension | 54 (70.1%) | 149 (72.3%) | 0.715 |
Diabetes | 25 (32.5%) | 57 (27.7%) | 0.429 |
Hyperlipidemia | 48 (62.3%) | 142 (68.9%) | 0.293 |
Smoking | 39 (50.6%) | 89 (43.2%) | 0.263 |
Previous stroke | 12 (15.6%) | 31 (15.0%) | .0.911 |
Peripheral artery disease | 30 (39.0%) | 77 (37.4%) | 0.807 |
Active cancer | 4 (5.2%) | 1 (0.5%) | 0.007 |
Deep vein thrombosis | 14 (18.2%) | 22 (10.7%) | 0.092 |
Stroke mechanism | |||
Large artery atherosclerosis | 18 (23.4%) | 60 (29.3%) | 0.008 |
Small vessel disease | 17 (22.1%) | 76 (37.1%) | |
Cardioembolism | 17 (22.1%) | 20 (9.8%) | |
Other determined | 0 (0.0%) | 2 (1.0%) | |
Undetermined | 25 (32.5%) | 47 (22.9%) | |
BMI (kg/m2) | 24 ± 4 | 24 ± 3 | 0.665 |
mRS before index stroke | 0.3 ± 0.8 | 0.2 ± 0.6 | 0.218 |
Initial NIHSS | 5.8 ± 4.5 | 4.0 ± 3.2 | < 0.001 |
Laboratory results | |||
AST (mg/dL) | 41 ± 4.9 | 41 ± 5.0 | 0.941 |
ALT (mg/dL) | 46 ± 13 | 43 ± 14 | 0.106 |
BUN (mg/dL) | 18 ± 9 | 17 ± 5 | 0.414 |
Creatinine (mg/dL) | 0.9 ± 0.3 | 0.8 ± 0.4 | 0.318 |
D-dimer (mg/dL) | 2.2 ± 2.1 | 0.3 ± 0.1 | < 0.001 |
FDP (μg/mL) | 10 ± 15 | 3 ± 2 | < 0.001 |
Thrombolysis | 11 (14.3) | 3 (1.5) | < 0.001 |
Concomitant antithrombotics | |||
Single antiplatelet | 54 (70.1) | 166 (80.6) | 0.150 |
Dual antiplatelet | 13 (16.9) | 25 (12.1) | |
Anticoagulation | 10 (13.) | 15 (7.3) | |