Skip to main content

Table 1 Patient characteristics

From: Factors associated with insufficient response to acute treatment of migraine in Japan: analysis of real-world data from the Adelphi Migraine Disease Specific Programme

 

Insufficient responders (N = 227)

Sufficient responders (N = 311)

Total (N = 538)

Age (years, mean ± SD)

43.6 ± 13.4

44.5 ± 14.1

44.1 ± 13.8

Female, n (%)

180 (79.3)

235 (75.6)

415 (77.1)

Smoking status: current or prior smoker, n (%)

45 (20.3)

71 (23.9)

116 (22.4)

Neurologist consultation, n (%)*

117 (51.5)

98 (31.5)

215 (40.0)

Migraine/headache specialista, n (%)*

103 (45.4)

101 (32.5)

204 (37.9)

Employed, n (%)

138 (63.0)

198 (64.5)

336 (63.9)

Number of migraine headache days/month, n (%)

 0–3

103 (59.9)

151 (63.7)

254 (62.1)

 4–7

44 (25.6)

58 (24.5)

102 (24.9)

  ≥ 8

25 (14.5)

28 (11.8)

53 (13.0)

Chronic/episodic migraine, n (%)*

 Chronic migraine

20 (8.8)

11 (3.6)

31 (5.9)

 Episodic migraine

206 (91.2)

291 (96.4)

497 (94.1)

Migraine with aura, n (%)

82 (36.1)

121 (38.9)

203 (37.7)

Family history of migraine: parent, n (%)

45 (20.5)

55 (17.8)

100 (18.9)

Rebound headache or medication-overuse headache, n (%)*

15 (6.6)

9 (2.9)

24 (4.5)

Tension-type headache, n (%) *

63 (27.8)

51 (16.4)

114 (21.2)

Comorbidity (yes), n (%)

103 (45.4)

149 (47.9)

252 (46.8)

 Hypertensionb

23 (22.3)

46 (30.9)

69 (27.4)

 Hyperlipidemiab

20 (19.4)

32 (21.5)

52 (20.6)

 Anxietyb

18 (17.5)

23 (15.4)

41 (16.3)

 Sleep disordersb

15 (14.6)

21 (14.1)

36 (14.3)

 Asthma/COPD/allergic rhinitisb

15 (14.6)

17 (11.4)

32 (12.7)

 Depressionb

13 (12.6)

11 (7.4)

24 (9.5)

 GI problems/dyspepsiab

10 (9.7)

19 (12.8)

29 (11.5)

 Otherb

16 (15.5)

22 (14.8)

38 (15.1)

 Cardiovascular disease,b,c

23 (22.3)

47 (31.5)

70 (27.8)

  1. Physician-reported data
  2. *p < 0.05 between insufficient responders and sufficient responders (variables with significant differences in bold). For categorical measures, chi-squared or Fisher’s exact test was used. For continuous measures, t-test was used
  3. aPatients visited migraine/headache specialists who were either neurologists (n = 164; 30.5% of patients) or internists (n = 40; 7.4% of patients)
  4. bPercentages calculated based on the respective number of patients in each group with any comorbidity. Percentages are calculated as proportion of non-missing data. Comorbidities listed are those occurring in ≥10% of patients experiencing a comorbidity. Chronic migraine was defined as (≥15 headache days per month [15]); episodic migraine was defined as not fulfilling chronic migraine criteria [16]
  5. cCardiovascular disease is a derived variable that includes angina (seen in 1/2 insufficient/sufficient responders, respectively), hypertension (data in table), ischemic heart disease (seen in 0/2 insufficient/sufficient responders, respectively), post myocardial infarction (no occurrences in either group, and congestive heart failure (no occurrences in either group)
  6. COPD chronic obstructive pulmonary disease; GI gastrointestinal; SD standard deviation