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Table 6 Canonical pathways modulated in the inferior horn of the lateral ventricles after stratification for Braak staging and amyloid plaque score. Identified canonical pathways generated from the list of significantly modulated proteins after stratifying for low vs high amyloid plaque score (low < 10 vs high > 10) and early vs late Braak staging (0-II vs IV-VI) using Ingenuity pathway analyses (IPA). FDR adjusted P value after Fischer’s test and Benjamin Hochberg correction following uploading of significantly regulated proteins into IPA (significant cut-off set at 0.01). Early vs late Braak staging (11 pathways identified), low vs high amyloid plaque score (14 pathways identified). Blue represents upregulated pathways and Red represents downregulated pathways

From: Molecular abnormalities in autopsied brain tissue from the inferior horn of the lateral ventricles of nonagenarians and Alzheimer disease patients