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Table 1 Clinical and laboratory data by group

From: Elevated plasma biomarkers of inflammation in acute ischemic stroke patients with underlying dementia

  AIS (n = 35) AIS + D (n = 8) χ2 p
Age 64.5 ± 14.1 85.8 ± 9.6   0.0003
Sex    0.73 0.39
 Male 27 (77%) 5 (63%)   
 Female 8 (23%) 3 (37%)   
Time from stroke onset to venipuncture (h) 44.4 ± 17.5 39.5 ± 20.9   0.53
Initial NIHSS 4.3 ± 4.3 11.9 ± 8.1   0.009
Other conditions
 Atrial arrhythmia 7 (20%) 6 (75%) 9.34 0.002
 Kidney disease 4 (11%) 0 (0%) 1.01 0.32
 Hyperlipidemia 21 (60%) 4 (50%) 0.27 0.61
 Heart failure 3 (9%) 4 (50%) 8.20 0.004
 Diabetes 7 (20%) 1 (3%) 0.24 0.62
 Coronary artery disease 5 (14%) 1 (13%) 0.02 0.90
 Obesity 2 (6%) 0 (0%) 0.48 0.49
 Hypothyroidism 3 (9%) 0 (0%) 0.74 0.39
 Smoking / COPD 6 (17%) 2 (25%) 0.27 0.61
 Gastritis / ulcer 4 (11%) 0 (0%) 1.01 0.32
 Parkinson’s disease 0 (0%) 1 (13%) 4.48 0.03
IL-6 (pg/mL) 0 (0–5.5) 11.5 (9.8–18.0)   0.002
CRP (mg/L) 3.5 (1.6–9.6) 19.8 (13.2–41.8)   0.003
S100B (ng/L) 55.0 (46.0–91.5) 94.5 (71.8–464)   0.065
CC3 (mg/dL) 130 (111–142) 111 (105–123)   0.16
  1. Note: Age is presented as mean ± standard deviation. Laboratory values are presented as median and range between 25th percentile and 75th percentile values, with between group comparisons performed using the Mann-Whitney U test