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Table 2 Exploratory analysis comparing the AIS + D group to a subgroup of AIS patients with similarly severe strokes

From: Elevated plasma biomarkers of inflammation in acute ischemic stroke patients with underlying dementia

  AIS + D (n = 8) mild AIS (n = 29) p severe AIS (n = 6) p
IL-6 (pg/mL) 11.5 (9.8–18.0) 0 (0–6.0) 0.009 0 (0–0) 0.012
CRP (mg/L) 19.8 (13.2–41.8) 3.0 (1.0–10.0) 0.004 4.3 (3.6–5.0) 0.033
  1. Note: Laboratory values are presented as median and range between 25th percentile and 75th percentile values, with between group comparisons between AIS + D and mild AIS or severe AIS controls performed using the Mann-Whitney U test. The mild AIS control group was comprised of AIS patients with NIHSS < 10; the severe AIS control group was comprised of AIS patients with NIHSS ≥10. Mean NIHSS in the severe AIS group was 12.3, similar to the mean NIHSS in the AIS + D group (11.9, Table 1)