Skip to main content

Table 2 Exploratory analysis comparing the AIS + D group to a subgroup of AIS patients with similarly severe strokes

From: Elevated plasma biomarkers of inflammation in acute ischemic stroke patients with underlying dementia

 

AIS + D (n = 8)

mild AIS (n = 29)

p

severe AIS (n = 6)

p

IL-6 (pg/mL)

11.5 (9.8–18.0)

0 (0–6.0)

0.009

0 (0–0)

0.012

CRP (mg/L)

19.8 (13.2–41.8)

3.0 (1.0–10.0)

0.004

4.3 (3.6–5.0)

0.033

  1. Note: Laboratory values are presented as median and range between 25th percentile and 75th percentile values, with between group comparisons between AIS + D and mild AIS or severe AIS controls performed using the Mann-Whitney U test. The mild AIS control group was comprised of AIS patients with NIHSS < 10; the severe AIS control group was comprised of AIS patients with NIHSS ≥10. Mean NIHSS in the severe AIS group was 12.3, similar to the mean NIHSS in the AIS + D group (11.9, Table 1)