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Table 3 Factors associated with good clinical outcome in patients with intracranial atherosclerotic stenosis (ICAS)-related occlusion

From: Immediate effects of first-line thrombectomy devices for intracranial atherosclerosis-related occlusion: stent retriever versus contact aspiration

 

Univariate analysis

Multivariate analysis

Poor outcome

(N = 66)

Good outcome

(N = 45)

P

Odds ratio (95% CI)

P

Demographics

 Age, years

68.7 ± 11.9

60.2 ± 14.2

0.001

0.956 (0.915–0.995)

0.035

 Sex, men

39 (59.1)

31 (68.9)

0.395

0.863 (0.287–2.542)

0.789

Risk factors

 Hypertension

46 (69.7)

25 (55.6)

0.186

  

 Diabetes mellitus

20 (30.3)

14 (31.1)

> 0.999

  

 Dyslipidemia

22 (33.3)

13 (28.9)

0.774

  

 Atrial fibrillation

12 (18.2)

12 (26.7)

0.406

  

 Smoker

20 (30.3)

19 (42.2)

0.276

  

Initial occlusion site

  

0.001

  

 Internal carotid artery

13 (19.7)

1 (2.2)

 

Ref

 

 Middle cerebral artery

36 (54.5)

39 (86.7)

 

12.544 (1.777–259.986)

0.030

 Vertebral/Basilar artery

17 (25.8)

5 (11.1)

 

5.021 (0.520–117.656)

0.206

Initial NIHSS score

19 (14–23)

12 (9–16)

< 0.001

0.830 (0.742–0.913)

< 0.001

ASPECTS scorea

7 (4–8)

8 (6–10)

0.005

  

Onset to door time, min

196 (120–421)

204 (82–457)

0.833

  

Door to puncture time, min

106 (81–130)

107 (89–123)

0.881

  

IV tPA

30 (45.5)

20 (44.4)

> 0.999

  

Stent retriever as first-line device

27 (40.9)

22 (48.9)

0.524

0.987 (0.346–2.770)

0.980

Primary successful reperfusion

35 (53.0)

30 (66.7)

0.217

  

Final successful reperfusion

51 (77.3)

40 (88.9)

0.190

5.479 (1.441–24.841)

0.018

Number of techniques

2 (2–3)

2 (1–3)

0.457

1.208 (0.643–2.293)

0.555

Laboratory findings

 Hemoglobin, g/dL

14.0 ± 1.9

14.0 ± 2.0

0.917

  

 White blood cells, ×109/L

11.2 ± 5.0

9.4 ± 3.8

0.036

0.910 (0.784–1.039)

0.186

 Platelets, ×109/L

242 ± 72

236 ± 65

0.616

  

Glucose, mmol/L

8.2 ± 3.1

8.4 ± 3.5

0.709

  
  1. aBaseline ASPECTS on quality imaging was evaluated in 81 patients (91.0% patients with anterior circulation infarction)
  2. NIHSS National Institutes of Health Stroke Scale; ASPECTS Alberta Stroke Program Early CT Score; IV tPA Intravenous tissue plasminogen activator