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Table 3 Clinical features of RLS patients with abdomen involvement

From: Restless abdomen: a spectrum or a phenotype variant of restless legs syndrome?

  Case 1 Case 2 Case 3 Case 4 Case 5 Case 6 Case 7 Case 8 Case 9 Case 10
Associated features
Family history +
Response to dopaminergic therapy + + + + + + + + + +
IRLSRS (scores) Severe(21) Severe (21) Severe (29) Very severe (35) Severe (27) Moderate (20) Very severe(31) Very severe(32) Severe (29) Very severe(32)
Classification Chronic-persistent Chronic-persistent Chronic-persistent Intermittent Chronic-persistent Chronic-persistent Chronic-persistent Chronic-persistent Chronic-persistent Chronic-persistent
RLS symptom fluctuation with seasonal trends Worse in cold weather Worse in wet weather U Worse in summer U U U U U U
Distribution of the sensations Front of thigh and abdomen Legs, arms and abdomen Upper thigh, genital area and abdomen Legs, arms, hip and abdomen Legs and abdomen Knee, popliteal fossa, calf and abdomen Abdomen Abdomen Chest and abdomen Legs and abdomen
Type of sensations Itching Crawling Soreness, formication and itching Indescribable discomfort Indescribable discomfort Itching and soreness Soreness Indescribable discomfort Itching Numbness
HAMA (scores) Possible anxiety(9) Without anxiety(5) Obvious anxiety(23) Obvious anxiety(25) Possible anxiety(9) Exist anxiety(15) Possible anxiety(12) Exist anxiety(20) Without anxiety(5) Obvious anxiety(21)
HAMD (scores) Possible depression(13) Possible depression(11) Exist depression(17) Exist depression(18) Possible depression(12) Exist depression(17) Exist depression(18) Possible depression(12) Without depression(4) Exist depression(14)
Therapy Pramipexol 0.25 mg/n Pramipexol 0.25 mg/n Pramipexol 0.25 mg/n and antidepressant Pramipexol 0.125 mg/n Pramipexol 0.25 mg/n Pramipexol 0.25 mg/n Pramipexol 0.25 mg/n and gabapentin 0.3 g/d Pramipexol 0.25 mg/n and gabapentin 0.3 g/d Pramipexol 0.25 mg/n and gabapentin 0.3 g/d Madopar 125 mg/d
  1. U unrelated, HAMA Hamilton Anxiety Scale, HAMD Hamilton Depression Scale