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Table 3 Clinical features of RLS patients with abdomen involvement

From: Restless abdomen: a spectrum or a phenotype variant of restless legs syndrome?

 

Case 1

Case 2

Case 3

Case 4

Case 5

Case 6

Case 7

Case 8

Case 9

Case 10

Associated features

Family history

–

–

–

+

–

–

–

–

–

–

Response to dopaminergic therapy

+

+

+

+

+

+

+

+

+

+

IRLSRS (scores)

Severe(21)

Severe (21)

Severe (29)

Very severe (35)

Severe (27)

Moderate (20)

Very severe(31)

Very severe(32)

Severe (29)

Very severe(32)

Classification

Chronic-persistent

Chronic-persistent

Chronic-persistent

Intermittent

Chronic-persistent

Chronic-persistent

Chronic-persistent

Chronic-persistent

Chronic-persistent

Chronic-persistent

RLS symptom fluctuation with seasonal trends

Worse in cold weather

Worse in wet weather

U

Worse in summer

U

U

U

U

U

U

Distribution of the sensations

Front of thigh and abdomen

Legs, arms and abdomen

Upper thigh, genital area and abdomen

Legs, arms, hip and abdomen

Legs and abdomen

Knee, popliteal fossa, calf and abdomen

Abdomen

Abdomen

Chest and abdomen

Legs and abdomen

Type of sensations

Itching

Crawling

Soreness, formication and itching

Indescribable discomfort

Indescribable discomfort

Itching and soreness

Soreness

Indescribable discomfort

Itching

Numbness

HAMA (scores)

Possible anxiety(9)

Without anxiety(5)

Obvious anxiety(23)

Obvious anxiety(25)

Possible anxiety(9)

Exist anxiety(15)

Possible anxiety(12)

Exist anxiety(20)

Without anxiety(5)

Obvious anxiety(21)

HAMD (scores)

Possible depression(13)

Possible depression(11)

Exist depression(17)

Exist depression(18)

Possible depression(12)

Exist depression(17)

Exist depression(18)

Possible depression(12)

Without depression(4)

Exist depression(14)

Therapy

Pramipexol 0.25 mg/n

Pramipexol 0.25 mg/n

Pramipexol 0.25 mg/n and antidepressant

Pramipexol 0.125 mg/n

Pramipexol 0.25 mg/n

Pramipexol 0.25 mg/n

Pramipexol 0.25 mg/n and gabapentin 0.3 g/d

Pramipexol 0.25 mg/n and gabapentin 0.3 g/d

Pramipexol 0.25 mg/n and gabapentin 0.3 g/d

Madopar 125 mg/d

  1. U unrelated, HAMA Hamilton Anxiety Scale, HAMD Hamilton Depression Scale