From: Restless abdomen: a spectrum or a phenotype variant of restless legs syndrome?
 | Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 | Case 7 | Case 8 | Case 9 | Case 10 |
---|---|---|---|---|---|---|---|---|---|---|
Associated features | ||||||||||
Family history | – | – | – | + | – | – | – | – | – | – |
Response to dopaminergic therapy | + | + | + | + | + | + | + | + | + | + |
IRLSRS (scores) | Severe(21) | Severe (21) | Severe (29) | Very severe (35) | Severe (27) | Moderate (20) | Very severe(31) | Very severe(32) | Severe (29) | Very severe(32) |
Classification | Chronic-persistent | Chronic-persistent | Chronic-persistent | Intermittent | Chronic-persistent | Chronic-persistent | Chronic-persistent | Chronic-persistent | Chronic-persistent | Chronic-persistent |
RLS symptom fluctuation with seasonal trends | Worse in cold weather | Worse in wet weather | U | Worse in summer | U | U | U | U | U | U |
Distribution of the sensations | Front of thigh and abdomen | Legs, arms and abdomen | Upper thigh, genital area and abdomen | Legs, arms, hip and abdomen | Legs and abdomen | Knee, popliteal fossa, calf and abdomen | Abdomen | Abdomen | Chest and abdomen | Legs and abdomen |
Type of sensations | Itching | Crawling | Soreness, formication and itching | Indescribable discomfort | Indescribable discomfort | Itching and soreness | Soreness | Indescribable discomfort | Itching | Numbness |
HAMA (scores) | Possible anxiety(9) | Without anxiety(5) | Obvious anxiety(23) | Obvious anxiety(25) | Possible anxiety(9) | Exist anxiety(15) | Possible anxiety(12) | Exist anxiety(20) | Without anxiety(5) | Obvious anxiety(21) |
HAMD (scores) | Possible depression(13) | Possible depression(11) | Exist depression(17) | Exist depression(18) | Possible depression(12) | Exist depression(17) | Exist depression(18) | Possible depression(12) | Without depression(4) | Exist depression(14) |
Therapy | Pramipexol 0.25 mg/n | Pramipexol 0.25 mg/n | Pramipexol 0.25 mg/n and antidepressant | Pramipexol 0.125 mg/n | Pramipexol 0.25 mg/n | Pramipexol 0.25 mg/n | Pramipexol 0.25 mg/n and gabapentin 0.3 g/d | Pramipexol 0.25 mg/n and gabapentin 0.3 g/d | Pramipexol 0.25 mg/n and gabapentin 0.3 g/d | Madopar 125 mg/d |