Table 2 Outcome measures and demographics, including at which time point the data will be collected
Outcome measures | Baseline | During intervention | Post-test | 16 week follow-up | |
|---|---|---|---|---|---|
Primary outcome measure | |||||
Criterion task | Letter memory running span | X | X | X | X |
Secondary outcome measures | |||||
Near transfer | |||||
Updating | n-back (1,2 and 3 back) | X | X | X | |
Digit memory running span | X | X | X | ||
Intermediate transfer | |||||
Perceptual and Psychomotor speed | Digit symbol | X | X | X | |
Perdue Pegboard | X | X | X | ||
Working memory | Digit span forward (WAIS IV) | X | X | X | |
Digit span backward (WAIS IV) | X | X | X | ||
Digit span sequencing(WAIS IV) | X | X | X | ||
Spatial span | X | X | X | ||
Inhibition | Stroop test (DKEFS) | X | X | X | |
Shifting | TMT A and B (DKEFS) | X | X | X | |
Far transfer | |||||
Episodic memory | Buschke SRP | X | X | X | |
Fluid reasoning | Martices (WAIS IV) | X | X | X | |
Other Pre-specified outcome measures | |||||
Subjective cognitive complaints | Prospective retrospective memory questionnaire | X | X | X | |
Depression and anxiety | Hospital Anxiety Depression scale (HAD) | X | X | X | |
Health status | Short form health survey (sf-36) | X | X | X | |
Sleep | Short version Karolinska Sleep questionaire | X | X | X | |
Function and well being | Parkinson’s Disease Questionnaire PDQ-39 | X | X | X | |
Fatigue | Checklist Individual Strength questionnaire (CIS) | X | X | X | |
Impulsivity and Risk taking | Urgency, Premediation, Perseverance and Sensationseeking (UPPS) | X | X | X | |
Balloon analog test | X | X | X | ||
Adherence (task engagement) | Self-assessed motivation and ability to stay focused during training | X | |||
Compliance | Number of participants finishing within time frame | X | |||
Expectation | Expectation of improvement in certain tasks | X | X | ||
Self-assessed improvement and adverse events | Evaluation of the training | X | X | ||
Demographics | |||||
Age | Age at baseline | X | |||
Gender | Gender | X | |||
Handedness | Lef/right | X | |||
Education level | Years of education | X | |||
Disease duration | Months | X | |||
Disease stage | Hoehn and Yahr stage | X | |||
Global cognition | Mini Mental State Examination (MMSE) | X | |||
Motor function | Unified Parkinson's Disease Rating Scale part III (UPDRS III) | X | |||
Disease laterality | Left/right | X | |||
Starting symptom and side | Symptom, Left/right | X | |||
Medication dose | LEDD | X | X | X | |
Vocabulary | Swedish four alternative multiple-choice synonym test (SRB 1) | X | |||
Cognitive status | MCI/NC | X | |||