Fig. 2

Example macular SD-OCT layer scan, SD-OCT and mfVEP parameters in microangiopathic ischemic stroke patients. An example macular volume SD-OCT layer scan is demonstrated through the fovea centralis with the red lines indicating the boundaries of the different retinal layers (a). In mfVEPs, amplitude (b) and first peak latency (c) between the microangiopathic ischemic stroke patients and the control group were analyzed. SD-OCT layers were measured in volume scans centered on the fovea and pRNFL was measured in peripapillary ring scans centered on the optic disc (d-l). The analysis revealed no significant difference of the retinal layer volume or thickness between the microangiopathic ischemic stroke patients and the control group. b.-l Boxplots with scatter plots are demonstrated for the microangiopathic ischemic stroke patients and the control group with n.s. indicating no significant difference. P-values < 0.05 were considered as statistically significant (GEE analysis with Bonferroni correction for multiple testing). The horizontal line in the boxplots represents the medians, the box the interquartile range (IQR) and the whiskers the minimum and maximum values (excluding outliers). Outliers (1.5–3.0 times outside the IQR) are presented as circles and extreme outliers (> 3.0 times outside the IQR) are presented as asterisks