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Fig. 1 | BMC Neurology

Fig. 1

From: A case report of complement C4B deficiency in a patient with steroid and IVIG-refractory anti-NMDA receptor encephalitis

Fig. 1

Molecular genetic characterization of the encephalitis patient with

antibodies against NMDA-receptor and his family members. a. Pulsed field gel electrophoresis (PFGE) of PmeI digested genomic DNA to show RP-C4-CYP21-TNX (RCCX) haplotypes; b. TaqI restriction fragment polymorphism (RFLP) to show details of RCCX structures with long (L) and short (S) C4 genes; c. PshAI/PvuII RFLP to show the presence and ratios of C4B and C4A genes; d. Immunofixation of EDTA-plasma to show polymorphisms of C4A and C4B proteins. A red arrow showed the presence of a C4B gene in panel C but no C4B protein in panel D. Data interpretation is tabulated in Table 1. Abbreviations: P, patient; F, father; M, mother; S1, stepbrother.

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