| Cerebrolysin n = 25 | Normal Saline n = 25 | OR (95% CI) |
---|---|---|---|
Global Functional Outcome at 6 months | |||
 GOSE, median (IQR) | 7 (5–8) | 7 (3–8) | NS |
 GOSE, favorable outcome, i.e. 5–8 | 19 | 17 | NS |
 mRS, median (IQR) | 1 (0–3) | 2 (0–4) | NS |
 mRS, favorable outcome, i.e. 0–3 | 22 | 17 | NS |
 BI, mean + SD | 91 + 28 | 90 + 24 | NS |
 BI > 75 | 23 | 18 | NS |
Global Functional Outcome at 3 months |  |  | NS |
 GOSE, median (IQR) | 5 (4–6) | 6 (3–7) |  |
 GOSE, favorable outcome, i.e. 5–8 | 15 | 16 | NS |
 mRS, median (IQR) | 2 (2–4) | 2 (2–5) | NS |
 mRS, favorable outcome, i.e. 0–3 | 18 | 17 | NS |
Mortality | |||
 6-month | 0 | 4 | 0.46 (0.33–0.63) |
 3-month | 0 | 4 | 0.46 (0.33–0.63) |
 30-day | 0 | 3 | NS |
Delayed Cerebral Ischemia | 11 | 12 | NS |
Cerebral Vasospasm | 3 | 7 | NS |
Cerebral infarction | 14 | 15 | NS |
Neurocognitive Performance at 6 months | |||
 MOCA, mean + SD | 21 + 9 | 21 + 8 | NS |
 NCSE, within average range | |||
  Orientation | 20 | 18 | NS |
  Attention | 21 | 18 | NS |
  Language comprehension | 18 | 16 | NS |
  Repetition | 15 | 10 | NS |
  Naming | 11 | 3 | 4.71 (1.10–20.00) |
  Constructional ability | 19 | 15 | NS |
  Memory | 12 | 9 | NS |
  Calculation | 19 | 17 | NS |
  Reasoning | 18 | 10 | 2.83 (1.01–9.61) |
  Judgment | 19 | 18 | NS |
Quality of Life at 6 months | |||
 SF-36® | |||
  Physical health score, mean + SD | 77 + 23 | 74 + 26 | NS |
  Mental health score, mean + SD | 69 + 25 | 69 + 21 | NS |
 SS-QoL, mean + SD | 4.5 + 0.7 | 4.5 + 0.6 | NS |
  Physical subscore, mean + SD | 4.6 + 0.8 | 4.5 + 0.7 | NS |
  Psychosocial subscore, mean + SD | 4.2 + 0.9 | 4.4 + 0.6 | NS |
Adverse Effects | 0 | 0 | NS |
Length of Hospital Stay, mean + SD | 33 + 15 | 39 + 32 | NS |