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Table 2 Timelines from onset to completion of the procedure

From: Mechanical thrombectomy: can it be safely delivered out of hours in the UK?

 

Total (n = 501)

In-hours (n = 211)*

Out-of-hours (n = 290)*

Adjusted mean difference (95% CI); p value**

Onset to door:

median; mean (SD)

108.0; 172.1 (195.1)

109.0; 169.8 (192.4)

107.0; 173.9 (197.5)

−2.6 (−37.2, 32.1); .884

Door to CT***:

median; mean (SD)

23.0; 34.1 (45.4)

21.0; 26.3 (22.7)

24.0; 40.0 (56.4)

14.9 (6.7, 23.2); <.001

CT to groin***:

median; mean (SD)

104.5; 113.0 (63.6)

89.5; 108.6 (71.8)

111.0; 116.3 (56.6)

8.7 (−3.0, 20.4); .143

Procedure time:

median; mean (SD)

55.0; 63.8 (42.5)

60.0; 69.5 (44.0)

53.0; 59.6 (40.9)

−10.8 (− 18.5, −3.2); .006

Door to groin:

median; mean (SD)

124.0; 138.2 (85.5)

110.0; 124.9 (73.7)

135.5; 148.0 (92.1)

25.6 (11.3, 39.9); <.001

Door to procedure end:

median; mean (SD)

184.0; 204.9 (105.4)

181.0; 196.5 (93.0)

188.5; 211.1 (113.4)

16.4 (−1.7, 34.4); .075

  1. CI confidence interval, SD standard deviation
  2. End of procedure is defined as the time of the final intracranial angiogram
  3. * Denominators differ between variables owing to missing or not applicable values
  4. ** Out-of-hours minus in-hours; a positive difference indicates time was greater for out-of-hours. Adjusted for age, sex, hypertension, atrial fibrillation, hyperlipidaemia, diabetes mellitus, previous stroke/TIA, coma, NIHSS at onset, anterior/posterior circulation lesion
  5. *** In total 40 patients were transferred straight to the neurointervention suite and received no imaging at RSUH prior to thrombectomy