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Table 4 Complications and outcomes up to 90 days

From: Mechanical thrombectomy: can it be safely delivered out of hours in the UK?

 

Total (n = 501)

In-hours (n = 211)

Out-of-hours (n = 290)

Adjusted difference (95% CI); p value*

NIHSS at 1 week: median; mean (SD)

7.0; 13.0 (14.0)

6.0; 12.1 (13.0)

7.0; 13.7 (14.6)

1.2 (− 1.2, 3.5); .334

Renal failure; n (%)

8 (1.6)

4 (1.9)

4 (1.4)

1.06 (0.22, 4.98); .946

Groin haematoma: n (%)

8 (1.6)

5 (2.4)

3 (1.0)

1.93 (0.43, 8.65); .392

Malignant middle cerebral artery syndrome: n (%)

44 (8.8)

12 (5.7)

32 (11.1)

0.52 (0.24, 1.14); .102

Hemicraniectomy: n (%)

13 (2.6)

5 (2.4)

8 (2.8)

1.42 (0.37, 5.44); .606

Symptomatic intracerebral haemorrhage: n (%)

8 (1.6)

3 (1.4)

5 (1.7)

0.85 (0.19, 3.73); .827

Subarachnoid haemorrhage: n (%)

45 (9.0)

22 (10.9)

23 (8.2)

1.28 (0.68, 2.41); .449

Deep vein thrombosis within 90 days: n (%)

12 (2.4)

7 (3.3)

5 (1.7)

1.95 (0.57, 6.64); .287

Pulmonary embolism within 90 days: n (%)

15 (3.0)

7 (3.3)

8 (2.8)

1.45 (0.48, 4.34); .509

Stroke within 90 days: n (%)

10 (2.0)

2 (1.0)

8 (2.8)

0.36 (0.07, 1.78); .210

Death at 90 days: n (%)

96 (19.2)

34 (16.1)

62 (21.4)

0.61 (0.36, 1.02); .061

Functional independence at 90 days: n (%)

234 (46.7)

100 (47.4)

134 (46.2)

1.07 (0.72, 1.58); .746

  1. Percentages are valid percentages (based on non-missing values). Functional independence is defined as modified Rankin Scale score of 0–2. Symptomatic intracerebral haemorrhage is defined as per the SITS-MOST criteria
  2. * Difference expressed as odds ratio, with out-of-hours as reference category, except for NIHSS, where it is mean difference (out-of-hours minus in-hours). Adjusted for age, sex, hypertension, atrial fibrillation, hyperlipidaemia, diabetes mellitus, previous stroke/TIA, coma, NIHSS at onset, anterior/posterior circulation lesion