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Table 4 Analyses of risk factors for Parkinson Disease in patients with and without Gout

From: Risk of Parkinson’s disease following gout: a population-based retrospective cohort study in Taiwan

Predictive variables

Univariate analysis

Multivariate analysis

HR (95% CI)

P value

HR (95% CI)

P value

Gout

1.36 (1.15–1.60)

<.001

1.01 (0.93–1.31)

.268

Age (< 65 = 0, ≥65 = 1)

8.20 (6.93–9.71)

<.001

4.41 (3.61–5.39)

<.001*

Sex (Male = 0, Female = 1)

1.37 (1.16–1.62)

<.001

0.90 (0.76–1.08)

.256

Comorbidities

 Diabetes mellitus

2.83 (2.38–3.36)

<.001

1.32 (1.08–1.60)

.006*

 Hypertension

4.62 (3.90–5.48)

<.001

1.85 (1.52–2.27)

<.001*

 Dyslipidemia

2.01 (1.69–2.38)

<.001

0.90 (0.74–1.09)

.281

 Cerebrovascular disease

4.63 (3.91–5.48)

<.001

2.04 (1.69–2.45)

<.001*

 Chronic lung disease

2.89 (2.38–3.52)

<.001

1.25 (1.02–1.53)

.035*

 Nephropathy

2.16 (1.77–2.63)

<.001

1.07 (0.86–1.32)

.563

 Chronic liver disease

1.80 (1.53–2.13)

<.001

1.23 (1.02–1.47)

.026*

 Autoimmune disease

1.66 (1.13–2.42)

.009

1.19 (0.81–1.75)

.369

Degree of urbanization

 Urban

Reference

 

Reference

 

 Suburban

1.34 (1.12–1.59)

.001

1.11 (0.92–1.33)

.276

 Rural

2.00 (1.57–2.54)

<.001

1.32 (1.02–1.71)

.033*

Income group

 High income

Reference

 

Reference

 

 Medium income

5.51 (3.59–8.44)

<.001

1.90 (1.21–2.99)

.005*

 Low income

3.94 (2.60–5.95)

<.001

0.98 (1.04–2.47)

.033*

 No income

1.30 (0.26–2.54)

.304

1.26 (0.76–2.10)

.369

  1. HR Indicates hazard ratio, CI Indicates confidence interval; * indicates statistical significance