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Table 2 Differences in clinical characteristics and baseline imaging profiles according to dichotomized clinical course based on malignant progression

From: Optic nerve sheath diameter change in prediction of malignant cerebral edema in ischemic stroke: an observational study

 

Malignant progressors

(n = 19)

Nonprogressors

(n = 39)

P-value

Clinical characteristics

 Sex, male

9 (47.4%)

22 (56.4%)

0.517

 Age

65 ± 19

69 ± 13

0.407

 Hypertension

15 (75.0%)

24 (60.0%)

0.251

 Diabetes mellitus

8 (40.0%)

10 (25.0%)

0.232

 Onset to door (min)

195 ± 240

173 ± 182

0.511

 Hypothermia

10 (52.6%)

21 (53.8%)

0.931

 Thrombolysis

12 (63.2%)

29 (74.4%)

0.379

 Endovascular treatment

19 (100.0%)

29 (74.4%)

0.015

 Successful reperfusion

11 (57.9%)

22 (56.4%)

0.915

 Outcomes (3 month mRS)

  

0.014

  0

0 (0.0%)

2 (5.1%)

 

  1

0 (0.0%)

2 (5.1%)

 

  2

0 (0.0%)

5 (12.8%)

 

  3

1 (5.3%)

4 (10.3%)

 

  4

2 (10.5%)

10 (25.6%)

 

  5

3 (15.8%)

9 (23.1)

 

  6

13 (68.4%)

7 (17.9%)

 

CTbaseline

 CT angiography occlusion

  

0.015

  Complex T

10 (52.6%)

6 (15.4%)

 

  Simple T

4 (21.1%)

11 (28.2%)

 

  MCA M1

3 (15.8%)

14 (35.9%)

 

  Tandem

0 (0.0%)

7 (17.9%)

 

  Proximal ICA

1 (5.3%)

0 (0.0%)

 

  Dissection

1 (5.3%)

1 (2.6%)

 

 Initial DWI volume (ml)

237 ± 109

144 ± 43

0.002

 ONSD (mm)

5.17 ± 0.55

5.37 ± 0.63

0.233

 ONSD/ETD ratio

22.84 ± 2.33%

23.60 ± 2.83%

0.316

 MLS (mm)

0.44 ± 0.78

0.37 ± 0.95

0.789

  1. Values are presented as mean ± SD, number (%), or median (interquartile range)
  2. mRS Modified Rankin Scale, CT Computed tomography, MCA Middle cerebral artery, ICA Internal carotid artery, DWI Diffusion weighted images, ONSD Optic nerve sheath diameter, ETD Eyeball transverse diameter, MLS Midline shift