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Table 1 Demographic and clinical characteristics of patients with and without MCE

From: A web based dynamic MANA Nomogram for predicting the malignant cerebral edema in patients with large hemispheric infarction

Parameter

Non-ME (N = 101)

ME (N = 41)

P

Age, y, (IQR)

58 (51 ~ 67)

64 (57 ~ 71)

0.005*

Gender, male, N (%)

70 (69.3)

26 (63.4)

0.497

Smoke, N (%)

53 (52.5)

21 (51.2)

0.892

Drink, N (%)

44 (43.6)

14 (34.1)

0.302

Hypertension, N (%)

50 (49.5)

21 (51.2)

0.853

Diabetes mellitus, N (%)

18 (17.8)

9 (22)

0.570

Previous stroke, N (%)

16 (15.8)

13 (31.7)

0.037*

Preexisting coronary heart disease, N (%)

9 (8.9)

10 (24.4)

0.018*

KAF

8 (7.9)

13 (31.7)

0.001*

Treatment, N (%)

 Conservative (reference)

79 (78.2)

34 (82.9)

 

 Intravenous thrombolysis

16 (15.8)

4 (9.8)

0.362

 Endovascular intervention

6 (5.9)

3 (7.3)

0.839

NIHSS (IQR)

18 (15 ~ 20)

21 (20 ~ 22)

<  0.001*

MLS, mm (IQR)

1.9 (3.6 ~ 5.1)

5.6 (4.9 ~ 8.1)

<  0.001*

Baseline temperature, °C (IQR)

36.5 (36.4 ~ 36.8)

36.5 (36.5 ~ 37.1)

0.170

ACA territory involvement, N (%)

9 (8.9)

18 (43.9)

<  0.001*

PCA territory involvement, N (%)

27 (26.7)

24 (58.5)

<  0.001*

Basal ganglia involvement, N (%)

60 (59.4)

37 (90.2)

0.001*

Cerebral hemisphere, right, N (%)

56 (55.4)

15 (36.6)

0.044*

Systolic pressure, mmHg, (IQR)

145 (127 ~ 166)

141 (120 ~ 159)

0.168

Diastolic pressure, mmHg, (IQR)

83 (73 ~ 95)

80 (74 ~ 92)

0.871

FBG, mmol/L, (IQR)

5.9 (5.4 ~ 6.8)

7.1 (5.8 ~ 9.2)

0.002*

HbA1c, %, (IQR)

5.6 (5.3 ~ 6.1)

5.7 (5.3 ~ 6.1)

0.378

  1. MCE: Malignant cerebral edema, IQR Interquartile range, KAF Previously known atrial fibrillation, NIHSS National Institutes of Health stroke scale, MLS Midline shift, ACA Anterior cerebral artery, PCA Posterior cerebral artery, FBG Baseline fasting blood glucose, HbA1c Glycosylated hemoglobin
  2. *p < 0.05 in univariate analysis were included in multivariable logistic regression models for adjustment