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Fig. 2 | BMC Neurology

Fig. 2

From: A case report of late-onset cerebellar ataxia associated with a rare p.R342W TGM6 (SCA35) mutation

Fig. 2

Genetic and bioinformatic analysis. a Electropherogram of TGM6 heterozygous c.1024C > T in the proband. b Schematic representation of TGM6 gene structure and TG6 protein structure, showing the localization of p.R342W. c Conservation among orthologous genes of the R342 amino acid (mutation site), with the colours used by the Clustal Omega multiple sequence alignment program (red = hydrophobic, light blue = positively charged, pink = negatively charged, light green = polar, aquamarine = aromatic, dark green = glycine, orange = proline) [4]

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