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Table 2 B/M-values after ex vivo irradiation by 2 Gy in patients and healthy individuals

From: Ex vivo radiosensitivity is increased in non-cancer patients taking valproate

  Healthy Individuals (n) Patients (n) p-value
Mean B/M-value (2 Gy) 0.415 ± 0.07 (62) 0.480 ± 0.09 (31) .001
< 0.500 B/M 88.7% (55) 45.2% (14) <.001
> 0.500 B/M 11.3% (7) 54.9% (14) <.001
> 0.600 B/M 0.0% (0) 9.7% (3) <.001
  1. Mean values of breaks per metaphase are given with standard deviations. Fractions of healthy individuals vs. patients with average B/M (B/M ≤ 0.500), increased (B/M > 0.500) and distinctly increased radiosensitivity (B/M > 0.600) are given