Ex vivo radiosensitivity is increased in non-cancer patients taking valproate

BMC Neurology

Table 3 Profiles of three patients and their radiosensitivity under different settings of VPA intake

	Patient 1	Patient 2	Patient 3
VPA-dosage per day (1) (mg)	0	0	500
VPA-dosage per day (2) (mg)	2400	3000	1500
B/M-value 2 Gy (1)	0.491	0.399	0.354
B/M-value 2 Gy (2)	0.576	0.522	0.630
Distance between time point (1) and (2)	72 h	48 h	72 h
Age	78	35	21
Sex	M	M	M
Height (cm)	n.a.	173	n.a.
Weight (kg)	80	72	86
Comedication	10	2	2

(1) Is the first time point with the specific VPA dosage and the first determination of radiation sensitivity and (2) is the second time point with the VPA dosage and the second determination of radiation sensitivity in identical patients

ISSN: 1471-2377