Table 1 Synopsis of clinical, radiologic, laboratory and therapeutic characteristics in 8 patients with BCS
Case | Age at onset (years) | Sex | Symptoms at BCS onset | BCS-type lesion size (cm) at onset | Pattern of BCS-type lesion Gd+ | Coexistence of brain MS-like plaques | Barkof criteria fulfillment at BCS onset | Spinal cord lesions at BCS onset | CSF OCBs | Time to follow-up from BCS onset (months) | Response to IVMP | Long-term Treatment |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 24 | M | right-sided hemiparesis and hemianaesthesia | 2.8 | Peripheral Gd + at outer layer | (+) | No | (−) | (+) | 85 | poor | CYC |
2 | 30 | F | dysarthria,left facial palsy, left hand dexterity problems | 3.6 | Peripheral ring-like Gd + at outer layer | (−) | No | (−) | (+) | 34 | poor | CYC |
3 | 41 | M | Wernicke’s aphasia and right-sided hemianaesthesia | 2.6 | Peripheral ring-like Gd + at outer two layers | (+) | No | (−) | Not tested | 132 | poor | 1st MTX 2nd GA |
4 | 18 | F | blurred vision | 3.1 | Peripheral incomplete ring-like Gd + at outer two layers | (+) | Yes | (−) | (+) | 16 | excellent | 1st GA, 2nd NTZ |
5 | 18 | F | right-sided hemiparesis | 2 | Peripheral ringlike Gd + at outer layer | (+) | Yes | (+) | Not tested | 127 | good | 1st IFN-beta-1b, 2nd NTZ |
6 | 26 | M | dysarthria | 3.6 | Peripheral incomplete ringlike Gd + at outer two layers | (+) | Yes | (−) | (−) | 23 | poor | RTX |
7 | 26 | F | gait instability, mild left hemiparesis | 1.7 | peripheral Gd + at outer layer | (+) | No | (+) | (+) | 29 | poor | RTX |
8 | 27 | M | left facial nerve palsy | 1.8 | partial ringlike Gd+ | (+) | No | (−) | (−) | 9 | poor | CYC |