From: Molecular exploration of paediatric intracranial germinomas from multi-ethnic Singapore
Variable | Number of patients | |
---|---|---|
Gender | Male | 10 |
(IG patients) | Female | 4 |
Gender | Male | 3 |
(Control group) | Female | 2 |
Ethnicity | Chinese | 9 |
Malay | 5 | |
Others | 0 | |
Age | IG patients | 14 (range 7 to 15 years old; median 12.4 years old) |
Control group | 5 (range 1 month to 7 years old; median 1.62 years old) | |
Location of tumour | Pineal | 6 |
Suprasellar | 3 | |
Basal ganglia | 2 | |
Intraventricular | 2 | |
Cerebral peduncle | 1 | |
Tumour seeding | Yes | 6 |
(at initial diagnosis) | No | 8 |
Tumour recurrence | Yes | 2 |
(at ≥ 5 years) | No | 12 |
Serum αFP (≤ 8 μg/L) | <  2 μg/L | 11 |
 | ≥ 2 μg/L | 3 (range 3 to 5 μg/L; median 3.67 μg/L) |
Serum βhcg (<  5 IU/L) | <  1.2 IU/L | 9 |
 | ≥ 1.2 IU/L | 4 (range 1.4 to 14 IU/L; median 6.6 IU/L) |
CSF αFP (<  2 μg/L) | <  2 μg/L | 14 |
CSF βhcg (<  1.2 IU/L) | <  1.2 IU/L | 6 |
 | ≥ 1.2 IU/ L | 8 (range 1.6 to 20 IU/L; median 9.32 IU/L) |