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Table 3 Baseline Characteristics of Patients with Chronic Subdural Hematoma according to postoperative BUN quartile

From: Elevated blood urea nitrogen is associated with recurrence of post-operative chronic subdural hematoma

Variables

BUN quartiles

quartile 1 n = 170(≤4.0)

quartile 2 n = 162(> 4.0,≤4.9)

quartile 3 n = 164(> 4.9,≤6.4)

quartile 4 n = 157(> 6.4)

P-value

BUN (mmol/L)

3.4 (3.0,3.7)

4.5 (4.3,4.8)

5.7 (5.3,6.0)

7.4 (6.9,8.3)

< 0.001

Demographic parameters

 Age (years)

68 (61,76)

72 (63,79)

73 (66,82)

76 (69,83)

< 0.001

 Gender, male, n (%)

140 (82.4%)

148 (91.4%)

141 (86.0%)

132 (84.1%)

0.103

 Current drinking, n (%)

61 (35.9%)

62 (38.3%)

58 (35.4%)

53 (33.8%)

0.866

 Current smoking, n (%)

68 (39.4%)

56 (34.6%)

63 (38.4%)

51 (32.5%)

0.526

 Baseline SBP (mmHg)

138.4 ± 19.4

139.3 ± 19.7

141.0 ± 20.6

142.5 ± 21.0

0.274

 Baseline DBP (mmHg)

79 (71,87)

79 (73,86)

77 (72,88)

78 (71,87)

0.984

Laboratory investigation

 Blood glucose (mmol/L)

5.5 (4.8,6.5)

5.6 (4.7,6.6)

5.6 (4.7,6.8)

5.4 (4.5,6.7)

0.818

 Cr (μmol/L)

60 (54,68)

66 (57,75)

69 (60,80)

74 (63,87)

< 0.001

 Leukocyte (X10^9/L)

7.00 (6.14,8.45)

6.97 (5.81,8.62)

6.98 (5.73,8.33)

6.77 (5.55,8.39)

0.677

 Neutrophil (X10^9/L)

4.78 (3.84,6.31)

4.68 (3.76,6.30)

4.52 (3.59,5.92)

4.52 (3.60,5.95)

0.369

 Lymphocyte (X10^9/L)

1.50 (1.10,1.80)

1.40 (1.10,1.71)

1.50 (1.11,1.87)

1.45 (1.10,1.81)

0.518

 Erythrocyte (X10^12/L)

4.30 ± 0.51

4.27 ± 0.50

4.24 ± 0.52

4.12 ± 0.52

0.008

 Hemoglobin (g/L)

133 (120,144)

133 (123,142)

132 (120,144)

130 (116,139)

0.047

 Platelet (X10^9/L)

219 (174,259)

206 (175,250)

203 (175,243)

201 (162,249)

0.183

 Prothrombin Time (s)

13.3 (12.7,13.8)

13.2 (12.9,13.9)

13.4 (12.9,13.9)

13.4 (12.9,14.1)

0.523

 INR

1.02 (0.97,1.07)

1.02 (0.97,1.08)

1.03 (0.97,1.08)

1.03 (0.97,1.10)

0.484

 Fibrinogen (g/L)

3.55 (3.11,4.38)

3.71 (3.10,4.35)

3.61 (2.97,4.18)

3.67 (3.12,4.26)

0.740

Comorbidities

 Hypertension, n (%)

61 (35.9%)

61 (37.7%)

60 (36.6%)

70 (44.6%)

0.355

 Diabetes mellitus, n (%)

18 (10.6%)

18 (11.1%)

17 (10.4%)

24 (15.3%)

0.480

 Cardiovascular disease, n (%)

9 (5.3%)

10 (6.2%)

11 (6.7%)

12 (7.6%)

0.853

Medication use

 Atorvastatin therapy, n (%)

124 (72.9%)

118 (72.8%)

114 (69.5%)

122 (77.7%)

0.427

 PAMBA therapy, n (%)

40 (23.5%)

45 (27.8%)

53 (32.3%)

51 (32.5%)

0.222

Hematoma location

    

0.367

 Unilateral left, n (%)

68 (40.0%)

82 (50.6%)

75 (45.7%)

63 (40.1%)

 

 Unilateral right, n (%)

62 (36.5%)

48 (29.6%)

55 (33.5%)

51 (32.5%)

 

 Bilateral, n (%)

40 (23.5%)

32 (19.8%)

34 (20.7%)

43 (27.4%)

 

GOS at discharge

    

0.042

 5, n (%)

160 (94.1%)

149 (92.0%)

152 (92.7%)

132 (84.1%)

 

 4, n (%)

8 (4.7%)

10 (6.2%)

8 (4.9%)

22 (14%)

 

 3, n (%)

2 (1.2%)

3 (1.9%)

4 (2.4%)

3 (1.9%)

 
  1. NOTE. SBP, systolic blood pressure; DBP, diastolic blood pressure; Cr, creatinine; INR, international normalized ratio; PAMBA, para-aminomethylbenzoic acid; BUN, blood urea nitrogen; GOS, Glasgow Outcome Scale