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Table 3 The comparison of AUC-ROC of the nomogram, HAT, SEDAN, SPAN-100, THRIVE and GRASPS for prognosis in the primary cohort and validation cohort

From: A new nomogram for individualized prediction of the probability of hemorrhagic transformation after intravenous thrombolysis for ischemic stroke patients

Scales Primary cohort Validation cohort
AUC-ROC 95%CI P value AUC-ROC 95%CI P value
Nomogram 0.9562 0.9221–0.9904   0.9854 0.9609–1.000  
HAT 0.8082 0.7099–0.9064 <0.01 0.6374 0.4183–0.8566 <0.01
SEDAN 0.7916 0.6807–0.9025 <0.01 0.6404 0.4992–0.7815 <0.01
SPAN-100 0.8174 0.7069–0.9279 <0.01 0.7339 0.5923–0.8755 <0.01
THRIVE 0.8641 0.7604–0.9678 0.0567 0.7763 0.6423–0.9103 <0.01
GRASPS 0.8239 0.7128–0.9350 0.0148 0.6170 0.4604–0.7735 <0.01
  1. Abbreviations: HAT Hemorrhage After Thrombolysis, SEDAN blood Sugar, Early infarct and hyper Dense cerebral artery sign on NCCT, Age, and NIHSS, SPAN-100 Stroke Prognostication using Age and NIHSS, THRIVE Totaled Health Risks in Vascular Events, and GRASPS Glucose, Race, Age, Sex, Systolic blood Pressure, and Severity of stroke, AUC-ROC area under the receiver operating characteristic curve