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Table 3 The comparison of AUC-ROC of the nomogram, HAT, SEDAN, SPAN-100, THRIVE and GRASPS for prognosis in the primary cohort and validation cohort

From: A new nomogram for individualized prediction of the probability of hemorrhagic transformation after intravenous thrombolysis for ischemic stroke patients

Scales

Primary cohort

Validation cohort

AUC-ROC

95%CI

P value

AUC-ROC

95%CI

P value

Nomogram

0.9562

0.9221–0.9904

 

0.9854

0.9609–1.000

 

HAT

0.8082

0.7099–0.9064

<0.01

0.6374

0.4183–0.8566

<0.01

SEDAN

0.7916

0.6807–0.9025

<0.01

0.6404

0.4992–0.7815

<0.01

SPAN-100

0.8174

0.7069–0.9279

<0.01

0.7339

0.5923–0.8755

<0.01

THRIVE

0.8641

0.7604–0.9678

0.0567

0.7763

0.6423–0.9103

<0.01

GRASPS

0.8239

0.7128–0.9350

0.0148

0.6170

0.4604–0.7735

<0.01

  1. Abbreviations: HAT Hemorrhage After Thrombolysis, SEDAN blood Sugar, Early infarct and hyper Dense cerebral artery sign on NCCT, Age, and NIHSS, SPAN-100 Stroke Prognostication using Age and NIHSS, THRIVE Totaled Health Risks in Vascular Events, and GRASPS Glucose, Race, Age, Sex, Systolic blood Pressure, and Severity of stroke, AUC-ROC area under the receiver operating characteristic curve